Dengue virus (DENV) is an arbovirus of the Flaviviridae family and is an enveloped virion
containing a positive sense single-stranded RNA genome. DENV causes dengue fever (DF) …

Innate myeloid cell (IMC) populations form an essential part of innate immunity. Flow
cytometric (FCM) monitoring of IMCs in peripheral blood (PB) has great clinical potential for …

Background Dengue is a vector-borne debilitating disease that is manifested as mild
dengue fever, dengue with warning signs, and severe dengue. Dengue infection provokes a …

Background Rapid diagnosis tests (RDTs) are easy to carry out, provide fast results, and
could potentially guide medical treatment decisions. We investigated the performance of a …

Little is known about the contribution of virus-specific and cross-reacting antibodies (Abs) or
the cellular immune response generated by a primary dengue (DENV) infection on the …

The clinical presentation of dengue virus (DENV) infection is variable. Severe complications
mainly result from exacerbated immune responses. Type I interferons (IFN-I) are important in …

During the acute febrile phase of dengue virus (DENV) infection, viremia can cause severe
systemic immune responses accompanied by hematologic disorders. This study …

The Aedes aegypti mosquito transmits both dengue virus (DENV) and Zika virus (ZIKV).
Individuals in endemic areas are at risk for infection with both viruses, as well as for …

Monocytes, one of the main target cells for dengue virus (DENV) infection, contribute to the
resolution of viremia and to pathogenesis. We performed a longitudinal study by a detailed …

Background Dendritic cells (DCs) are specialized antigen-presenting cells known to bridge
innate and adaptive immune reactions. However, the relationship between circulating DCs …