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Copper homeostasis and cuproptosis in health and disease
L Chen, J Min, F Wang - Signal transduction and targeted therapy, 2022 - nature.com
As an essential micronutrient, copper is required for a wide range of physiological processes
in virtually all cell types. Because the accumulation of intracellular copper can induce …
in virtually all cell types. Because the accumulation of intracellular copper can induce …
[HTML][HTML] The multifaceted roles of copper in cancer: A trace metal element with dysregulated metabolism, but also a target or a bullet for therapy
Simple Summary Copper is an essential element for human life. However, its redox activity
can be detrimental for the cell that developed highly coordinated pathways to chelate and …
can be detrimental for the cell that developed highly coordinated pathways to chelate and …
Cystathionine-β-synthase: molecular regulation and pharmacological inhibition
Cystathionine-β-synthase (CBS), the first (and rate-limiting) enzyme in the transsulfuration
pathway, is an important mammalian enzyme in health and disease. Its biochemical …
pathway, is an important mammalian enzyme in health and disease. Its biochemical …
[HTML][HTML] A comprehensive review on the anti-cancer effects of oleuropein
In Mediterranean cuisine and culture, olive oil and olive fruits play a significant role. Many
people believe that those who consume olive oil and its fruit live longer and have a …
people believe that those who consume olive oil and its fruit live longer and have a …
[HTML][HTML] Copper complexes as anticancer agents targeting topoisomerases I and II
C Molinaro, A Martoriati, L Pelinski, K Cailliau - Cancers, 2020 - mdpi.com
Simple Summary Organometallics, such as copper compounds, are cancer
chemotherapeutics used alone or in combination with other drugs. One small group of …
chemotherapeutics used alone or in combination with other drugs. One small group of …
The role of chosen essential elements (Zn, Cu, Se, Fe, Mn) in food for special medical purposes (FSMPs) dedicated to oncology patients—critical review: state-of-the …
The sco** review aimed to characterise the role of selected essential elements (Zn, Cu,
Se, Fe, Mn) in food for special medical purposes (FSMPs) aimed at oncology patients. The …
Se, Fe, Mn) in food for special medical purposes (FSMPs) aimed at oncology patients. The …
[HTML][HTML] Copper (II) phenanthroline-based complexes as potential anticancer drugs: a walkthrough on the mechanisms of action
Copper is an endogenous metal ion that has been studied to prepare a new antitumoral
agent with less side-effects. Copper is involved as a cofactor in several enzymes, in ROS …
agent with less side-effects. Copper is involved as a cofactor in several enzymes, in ROS …
Targeting copper in cancer imaging and therapy: a new theragnostic agent
G Capriotti, A Piccardo, E Giovannelli… - Journal of Clinical …, 2022 - mdpi.com
Copper is required for cancer cell proliferation and tumor angiogenesis. Copper-64
radionuclide (64Cu), a form of copper chloride (64CuCl2), is rapidly emerging as a …
radionuclide (64Cu), a form of copper chloride (64CuCl2), is rapidly emerging as a …
A new, extremely sensitive, turn-off optical sensor utilizing Schiff base for fast detection of Cu (II)
Throughout this research, a unique optical sensor for detecting one of the most dangerous
heavy metal ions, Cu (II), was designed and developed. The (4-mercaptophenyl) …
heavy metal ions, Cu (II), was designed and developed. The (4-mercaptophenyl) …
[HTML][HTML] Curcumin and its derivatives induce apoptosis in human cancer cells by mobilizing and redox cycling genomic copper ions
Turmeric spice contains curcuminoids, which are polyphenolic compounds found in the
Curcuma longa plant's rhizome. This class of molecules includes curcumin …
Curcuma longa plant's rhizome. This class of molecules includes curcumin …