Molecular insights of exercise therapy in disease prevention and treatment

D Walzik, TY Wences Chirino, P Zimmer… - Signal transduction and …, 2024 - nature.com
Despite substantial evidence emphasizing the pleiotropic benefits of exercise for the
prevention and treatment of various diseases, the underlying biological mechanisms have …

[HTML][HTML] Nutritional and exercise interventions in cancer-related cachexia: an extensive narrative review

VJ Clemente-Suárez, L Redondo-Flórez… - International Journal of …, 2022 - mdpi.com
One of the common traits found in cancer patients is malnutrition and cachexia, which affects
between 25% to 60% of the patients, depending on the type of cancer, diagnosis, and …

Exercise-downregulated CD300E acted as a negative prognostic implication and tumor-promoted role in pan-cancer

Z Luo, J Zhu, R Xu, R Wan, Y He, Y Chen… - Frontiers in …, 2024 - frontiersin.org
Background Breast cancer ranks as one of the most prevalent malignancies among women
globally, with increasing incidence rates. Physical activity, particularly exercise, has …

[HTML][HTML] Molecular mechanisms of cancer cachexia. Role of exercise training

E Tamayo-Torres, A Garrido, R de Cabo… - Molecular Aspects of …, 2024 - Elsevier
Cancer-associated cachexia represents a multifactorial syndrome mainly characterized by
muscle mass loss, which causes both a decrease in quality of life and anti-cancer therapy …

[HTML][HTML] Skeletal muscle atrophy, regeneration, and dysfunction in heart failure: impact of exercise training

H Gallagher, PW Hendrickse, MG Pereira… - Journal of Sport and …, 2023 - Elsevier
This review highlights some established and some more contemporary mechanisms
responsible for heart failure (HF)-induced skeletal muscle wasting and weakness. We first …

Sarcopenic obesity: what about in the cancer setting?

GG Cappellari, C Brasacchio, D Laudisio, C Lubrano… - Nutrition, 2022 - Elsevier
Growing evidence suggests that changes in muscle mass and function may further
contribute to health risk assessment in individuals who are obese. As numbers for both …

Exercise-augmented THSD7B exhibited a positive prognostic implication and tumor-suppressed functionality in pan-cancer

Z Luo, J Zhu, Z Fang, R Xu, R Wan, Y He… - Frontiers in …, 2024 - frontiersin.org
Background Breast cancer, one of the most prevalent malignancies among women
worldwide, has rising incidence rates. Physical activity, particularly exercise, has emerged …

Physical exercise at the crossroad between muscle wasting and the immune system: implications for lung cancer cachexia

F Cortiula, LEL Hendriks… - Journal of cachexia …, 2022 - Wiley Online Library
Cachexia is a syndrome characterized by involuntary weight loss and wasting of skeletal
muscle mass. It is associated with worse overall survival and quality of life. The cancer …

Impact of cancer cachexia on cardiac and skeletal muscle: role of exercise training

C Bordignon, BS Dos Santos, DD Rosa - Cancers, 2022 - mdpi.com
Simple Summary Cachexia is a syndrome that can be present in many patients diagnosed
with cancer, especially in those with metastatic or very advanced tumors. The patient may …

Physical performance and plasma metabolic profile as potential prognostic factors in metastatic lung cancer patients

W das Neves, CRR Alves, G Dos Santos… - European journal of …, 2024 - Wiley Online Library
Background Low physical performance is associated with higher mortality rate in multiple
pathological conditions. Here, we aimed to determine whether body composition and …