Digital biomarkers for Alzheimer's disease: the mobile/wearable devices opportunity
Alzheimer's Disease (AD) represents a major and rapidly growing burden to the healthcare
ecosystem. A growing body of evidence indicates that cognitive, behavioral, sensory, and …
ecosystem. A growing body of evidence indicates that cognitive, behavioral, sensory, and …
Contact lens sensors in ocular diagnostics
Contact lenses as a minimally invasive platform for diagnostics and drug delivery have
emerged in recent years. Contact lens sensors have been developed for analyzing the …
emerged in recent years. Contact lens sensors have been developed for analyzing the …
Spontaneous eye blink rate as predictor of dopamine-related cognitive function—A review
An extensive body of research suggests the spontaneous eye blink rate (EBR) is a non-
invasive indirect marker of central dopamine (DA) function, with higher EBR predicting …
invasive indirect marker of central dopamine (DA) function, with higher EBR predicting …
[HTML][HTML] Look into my eyes: What can eye-based measures tell us about the relationship between physical activity and cognitive performance?
Background There is a growing interest to understand the neurobiological mechanisms that
drive the positive associations of physical activity and fitness with measures of cognitive …
drive the positive associations of physical activity and fitness with measures of cognitive …
Spontaneous eye blink rate: An index of dopaminergic component of sustained attention and fatigue
A Maffei, A Angrilli - International Journal of Psychophysiology, 2018 - Elsevier
Blink rate is a behavioral index highly correlated with frontostriatal dopaminergic activity.
The present research was aimed at studying the modulation of spontaneous blink rate in …
The present research was aimed at studying the modulation of spontaneous blink rate in …
mEBAL: A multimodal database for eye blink detection and attention level estimation
This work presents mEBAL, a multimodal database for eye blink detection and attention
level estimation. The eye blink frequency is related to the cognitive activity and automatic …
level estimation. The eye blink frequency is related to the cognitive activity and automatic …
Blink: characteristics, controls, and relation to dry eyes
JD Rodriguez, KJ Lane, GW Ousler III… - Current eye …, 2018 - Taylor & Francis
Blink is a complex phenomenon that is profoundly affected by diverse endogenous and
exogenous stimuli. It has been studied in the context of cognition, emotional, and …
exogenous stimuli. It has been studied in the context of cognition, emotional, and …
Dementia clinical trial implications of mild behavioral impairment
The World Alzheimer Report 2016 estimated that 47 million people are living with dementia
worldwide (Alzheimer's Disease International, 2016). In the inaugural World Health …
worldwide (Alzheimer's Disease International, 2016). In the inaugural World Health …
Dopamine and executive function: Increased spontaneous eye blink rates correlate with better set-shifting and inhibition, but poorer updating
T Zhang, D Mou, C Wang, F Tan, Y Jiang… - International Journal of …, 2015 - Elsevier
The central dopamine system (DA) has a significant role in the executive function (EF). The
spontaneous eye blink rate (EBR) is an effective clinical and non-invasive measure, which is …
spontaneous eye blink rate (EBR) is an effective clinical and non-invasive measure, which is …
Affective computing for late-life mood and cognitive disorders
Affective computing (also referred to as artificial emotion intelligence or emotion AI) is the
study and development of systems and devices that can recognize, interpret, process, and …
study and development of systems and devices that can recognize, interpret, process, and …