The 2020 WHO classification of tumors of bone: an updated review

JH Choi, JY Ro - Advances in anatomic pathology, 2021 - journals.lww.com
Bone tumors are a rare and heterogeneous group of neoplasms that occur in the bone. The
diversity and considerable morphologic overlap of bone tumors with other mesenchymal …

The emerging complexity of gene fusions in cancer

F Mertens, B Johansson, T Fioretos… - Nature Reviews Cancer, 2015 - nature.com
Structural chromosome rearrangements may result in the exchange of coding or regulatory
DNA sequences between genes. Many such gene fusions are strong driver mutations in …

[PDF][PDF] Bone sarcomas: ESMO–EURACAN–GENTURIS–ERN PaedCan Clinical Practice Guideline for diagnosis, treatment and follow-up

SJ Strauss, AM Frezza, N Abecassis, J Bajpai… - Annals of …, 2021 - Elsevier
Highlights•This Clinical Practice Guideline provides key recommendations on the
management of bone sarcomas.•Recommendations have been agreed following a …

Update from the 4th edition of the World Health Organization classification of head and neck tumours: odontogenic and maxillofacial bone tumors

JM Wright, M Vered - Head and neck pathology, 2017 - Springer
The 4th edition of the World Health Organization's Classification of Head and Neck Tumours
was published in January of 2017. This article provides a summary of the changes to …

The evolving classification of soft tissue tumours–an update based on the new 2013 WHO classification

CDM Fletcher - Histopathology, 2014 - Wiley Online Library
The new W orld H ealth O rganization (WHO) classification of soft tissue tumours was
published in early 2013, almost 11 years after the previous edition. While the number of …

Sarcoma classification: an update based on the 2013 World Health Organization Classification of Tumors of Soft Tissue and Bone

LA Doyle - Cancer, 2014 - Wiley Online Library
The 2013 World Health Organization Classification of Tumors of Soft Tissue and Bone
incorporates changes in tumor classification, as well as new genetic insights into the …

[HTML][HTML] Identifying patients with NTRK fusion cancer

JP Solomon, R Benayed, JF Hechtman, M Ladanyi - Annals of Oncology, 2019 - Elsevier
Due to the efficacy of tropomyosin receptor kinase (TRK) inhibitor therapy and the recent
Food and Drug Administration approval of larotrectinib, it is now clinically important to …

Ewing sarcoma and Ewing-like tumors

M Sbaraglia, A Righi, M Gambarotti, AP Dei Tos - Virchows Archiv, 2020 - Springer
Ewing sarcoma (ES) and Ewing-like sarcomas are highly aggressive round cell
mesenchymal neoplasms, most often occurring in children and young adults. The …

Detection of NTRK Fusions: Merits and Limitations of Current Diagnostic Platforms

JP Solomon, JF Hechtman - Cancer research, 2019 - AACR
Oncogenic fusions involving NTRK1, NTRK2, and NTRK3 with various partners are
diagnostic of infantile fibrosarcoma and secretory carcinoma yet also occur in lower …

Advances in sarcoma genomics and new therapeutic targets

BS Taylor, J Barretina, RG Maki, CR Antonescu… - Nature Reviews …, 2011 - nature.com
Increasingly, human mesenchymal malignancies are being classified by the abnormalities
that drive their pathogenesis. Although many of these aberrations are highly prevalent within …