Recent advance on carbamate-based cholinesterase inhibitors as potential multifunctional agents against Alzheimer's disease
Abstract Alzheimer's disease (AD), as the fourth leading cause of death among the elderly
worldwide, has brought enormous challenge to the society. Due to its extremely complex …
worldwide, has brought enormous challenge to the society. Due to its extremely complex …
Glutamate and GABA in microglia-neuron cross-talk in Alzheimer's disease
GA Czapski, JB Strosznajder - International Journal of Molecular Sciences, 2021 - mdpi.com
The physiological balance between excitation and inhibition in the brain is significantly
affected in Alzheimer's disease (AD). Several neuroactive compounds and their signaling …
affected in Alzheimer's disease (AD). Several neuroactive compounds and their signaling …
Exposure to environmental arsenic and emerging risk of Alzheimer's disease: perspective mechanisms, management strategy, and future directions
Alzheimer's disease (AD) is one of the most prevailing neurodegenerative diseases,
characterized by memory dysfunction and the presence of hyperphosphorylated tau and …
characterized by memory dysfunction and the presence of hyperphosphorylated tau and …
Modulatory effects of autophagy on APP processing as a potential treatment target for Alzheimer's disease
Alzheimer's disease (AD) is characterized by the formation of intracellular aggregate
composed of heavily phosphorylated tau protein and extracellular deposit of amyloid-β (Aβ) …
composed of heavily phosphorylated tau protein and extracellular deposit of amyloid-β (Aβ) …
Stem cell therapy for Alzheimer's disease: An overview of experimental models and reality
C Qin, K Wang, L Zhang, L Bai - Animal models and …, 2022 - Wiley Online Library
Alzheimer's disease (AD) is a neurodegenerative disorder. The pathology of AD is
characterized by extracellular amyloid beta (Aβ) plaques, neurofibrillary tangles composed …
characterized by extracellular amyloid beta (Aβ) plaques, neurofibrillary tangles composed …
Formulation development, characterization and antifungal evaluation of chitosan NPs for topical delivery of voriconazole in vitro and ex vivo
This study aims to develop chitosan-based voriconazole nanoparticles (NPs) using spray-
drying technique. The effect of surfactants and polymers on the physicochemical properties …
drying technique. The effect of surfactants and polymers on the physicochemical properties …
Inhibition of Butyrylcholinesterase and Human Monoamine Oxidase-B by the Coumarin Glycyrol and Liquiritigenin Isolated from Glycyrrhiza uralensis
GS Jeong, MG Kang, JY Lee, SR Lee, D Park, ML Cho… - Molecules, 2020 - mdpi.com
Eight compounds were isolated from the roots of Glycyrrhiza uralensis and tested for
cholinesterase (ChE) and monoamine oxidase (MAO) inhibitory activities. The coumarin …
cholinesterase (ChE) and monoamine oxidase (MAO) inhibitory activities. The coumarin …
Piperidine nucleus as a promising scaffold for alzheimer's disease: current landscape and future perspective
Heterocycles and their derivatives hold an important place in medicinal chemistry due to
their vast therapeutic and pharmacological significance and wider implications in drug …
their vast therapeutic and pharmacological significance and wider implications in drug …
In Vitro and In Silico Evaluation of Anticholinesterase and Antidiabetic Effects of Furanolabdanes and Other Constituents from Graptophyllum pictum (Linn.) Griffith
NT Metiefeng, AN Tamfu, M Fotsing Tagatsing… - Molecules, 2023 - mdpi.com
Graptophyllum pictum is a tropical plant noticeable for its variegated leaves and exploited for
various medicinal purposes. In this study, seven compounds, including three furanolabdane …
various medicinal purposes. In this study, seven compounds, including three furanolabdane …
Prospects of marine sterols against pathobiology of Alzheimer's disease: Pharmacological insights and technological advances
Alzheimer's disease (AD) is a degenerative brain disorder characterized by a progressive
decline in memory and cognition, mostly affecting the elderly. Numerous functional …
decline in memory and cognition, mostly affecting the elderly. Numerous functional …