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Machine learning for antimicrobial peptide identification and design
Artificial intelligence (AI) and machine learning (ML) models are being deployed in many
domains of society and have recently reached the field of drug discovery. Given the …
domains of society and have recently reached the field of drug discovery. Given the …
Identification of antimicrobial peptides from the human gut microbiome using deep learning
The human gut microbiome encodes a large variety of antimicrobial peptides (AMPs), but
the short lengths of AMPs pose a challenge for computational prediction. Here we combined …
the short lengths of AMPs pose a challenge for computational prediction. Here we combined …
[HTML][HTML] Enhancing antimicrobial peptide activity through modifications of charge, hydrophobicity, and structure
P Gagat, M Ostrówka, A Duda-Madej… - International Journal of …, 2024 - mdpi.com
Antimicrobial peptides (AMPs) are emerging as a promising alternative to traditional
antibiotics due to their ability to disturb bacterial membranes and/or their intracellular …
antibiotics due to their ability to disturb bacterial membranes and/or their intracellular …
sAMPpred-GAT: prediction of antimicrobial peptide by graph attention network and predicted peptide structure
K Yan, H Lv, Y Guo, W Peng, B Liu - Bioinformatics, 2023 - academic.oup.com
Abstract Motivation Antimicrobial peptides (AMPs) are essential components of therapeutic
peptides for innate immunity. Researchers have developed several computational methods …
peptides for innate immunity. Researchers have developed several computational methods …
Comprehensive assessment of machine learning-based methods for predicting antimicrobial peptides
Antimicrobial peptides (AMPs) are a unique and diverse group of molecules that play a
crucial role in a myriad of biological processes and cellular functions. AMP-related studies …
crucial role in a myriad of biological processes and cellular functions. AMP-related studies …
[HTML][HTML] Discovery of antimicrobial peptides in the global microbiome with machine learning
Novel antibiotics are urgently needed to combat the antibiotic-resistance crisis. We present a
machine-learning-based approach to predict antimicrobial peptides (AMPs) within the global …
machine-learning-based approach to predict antimicrobial peptides (AMPs) within the global …
Machine learning prediction of antimicrobial peptides
Antibiotic resistance constitutes a global threat and could lead to a future pandemic. One
strategy is to develop a new generation of antimicrobials. Naturally occurring antimicrobial …
strategy is to develop a new generation of antimicrobials. Naturally occurring antimicrobial …
Benchmarks in antimicrobial peptide prediction are biased due to the selection of negative data
Antimicrobial peptides (AMPs) are a heterogeneous group of short polypeptides that target
not only microorganisms but also viruses and cancer cells. Due to their lower selection for …
not only microorganisms but also viruses and cancer cells. Due to their lower selection for …
A novel family of defensin-like peptides from Hermetia illucens with antibacterial properties
Background The world faces a major infectious disease challenge. Interest in the discovery,
design, or development of antimicrobial peptides (AMPs) as an alternative approach for the …
design, or development of antimicrobial peptides (AMPs) as an alternative approach for the …
Perspectives in searching antimicrobial peptides (AMPs) produced by the microbiota
L Gallardo-Becerra, M Cervantes-Echeverría… - Microbial Ecology, 2024 - Springer
Abstract Changes in the structure and function of the microbiota are associated with various
human diseases. These microbial changes can be mediated by antimicrobial peptides …
human diseases. These microbial changes can be mediated by antimicrobial peptides …