Pharmacological and non-pharmacological interventions to prevent delirium in critically ill patients: a systematic review and network meta-analysis

LD Burry, W Cheng, DR Williamson, NK Adhikari… - Intensive care …, 2021 - Springer
Purpose To compare the effects of prevention interventions on delirium occurrence in
critically ill adults. Methods MEDLINE, Embase, PsychINFO, CINAHL, Web of Science …

[PDF][PDF] ICU delirium—a diagnostic and therapeutic challenge in the intensive care unit

K Kotfis, A Marra, EW Ely - Anaesthesiology intensive therapy, 2018 - termedia.pl
ICU delirium is a common medical problem occurring in patients admitted to the intensive
care units (ICUs). Studies have shown that ICU delirium is associated with increased …

Clinical practice guidelines for the prevention and management of pain, agitation/sedation, delirium, immobility, and sleep disruption in adult patients in the ICU

JW Devlin, Y Skrobik, C Gélinas… - Critical care …, 2018 - journals.lww.com
Objective: To update and expand the 2013 Clinical Practice Guidelines for the Management
of Pain, Agitation, and Delirium in Adult Patients in the ICU. Design:

Dexmedetomidine for prevention of delirium in elderly patients after non-cardiac surgery: a randomised, double-blind, placebo-controlled trial

X Su, ZT Meng, XH Wu, F Cui, HL Li, DX Wang, X Zhu… - The Lancet, 2016 - thelancet.com
Background Delirium is a postoperative complication that occurs frequently in patients older
than 65 years, and presages adverse outcomes. We investigated whether prophylactic low …

Dexmedetomidine for reduction of atrial fibrillation and delirium after cardiac surgery (DECADE): a randomised placebo-controlled trial

A Turan, A Duncan, S Leung, N Karimi, J Fang, G Mao… - The Lancet, 2020 - thelancet.com
Background Atrial fibrillation and delirium are common consequences of cardiac surgery.
Dexmedetomidine has unique properties as sedative agent and might reduce the risk of …

Low-dose nocturnal dexmedetomidine prevents ICU delirium. A randomized, placebo-controlled trial

Y Skrobik, MS Duprey, NS Hill… - American journal of …, 2018 - atsjournals.org
Rationale: Dexmedetomidine is associated with less delirium than benzodiazepines and
better sleep architecture than either benzodiazepines or propofol; its effect on delirium and …

Dexmedetomidine versus propofol sedation reduces delirium after cardiac surgery

G Djaiani, N Silverton, L Fedorko, J Carroll… - …, 2016 - ingentaconnect.com
Background: Postoperative delirium (POD) is a serious complication after cardiac surgery.
Use of dexmedetomidine to prevent delirium is controversial. The authors hypothesized that …

Perioperative neurocognitive disorders: a narrative review focusing on diagnosis, prevention, and treatment

H Kong, LM Xu, DX Wang - CNS Neuroscience & therapeutics, 2022 - Wiley Online Library
Perioperative neurocognitive disorders (NCDs) refer to neurocognitive abnormalities
detected during the perioperative periods, including preexisting cognitive impairment …

Executive summary: clinical practice guidelines for the prevention and management of pain, agitation/sedation, delirium, immobility, and sleep disruption in adult …

JW Devlin, Y Skrobik, C Gélinas… - Critical care …, 2018 - journals.lww.com
Clinical Practice Guidelines for the Prev... : Critical Care Medicine Executive Summary: Clinical
Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium …

Sleep and circadian rhythm in critical illness

I Telias, ME Wilcox - Annual Update in Intensive Care and Emergency …, 2019 - Springer
Sleep is controlled by two major regulatory systems: a circadian system that drives 24-h
periodicity (Process C), and a homeostatic system (Process S) that ensures adequate …