DNA origami: scaffolds for creating higher order structures

F Hong, F Zhang, Y Liu, H Yan - Chemical reviews, 2017 - ACS Publications
DNA has become one of the most extensively used molecular building blocks for
engineering self-assembling materials. DNA origami is a technique that uses hundreds of …

Prediction and control in DNA nanotechnology

M DeLuca, S Sensale, PA Lin, G Arya - ACS applied bio materials, 2023 - ACS Publications
DNA nanotechnology is a rapidly develo** field that uses DNA as a building material for
nanoscale structures. Key to the field's development has been the ability to accurately …

How we make DNA origami

KF Wagenbauer, FAS Engelhardt, E Stahl… - …, 2017 - Wiley Online Library
DNA origami has attracted substantial attention since its invention ten years ago, due to the
seemingly infinite possibilities that it affords for creating customized nanoscale objects …

Direct simulation of the self-assembly of a small DNA origami

BEK Snodin, F Romano, L Rovigatti, TE Ouldridge… - ACS …, 2016 - ACS Publications
By using oxDNA, a coarse-grained nucleotide-level model of DNA, we are able to directly
simulate the self-assembly of a small 384-base-pair origami from single-stranded scaffold …

The sequence of events during folding of a DNA origami

F Schneider, N Möritz, H Dietz - Science advances, 2019 - science.org
We provide a comprehensive reference dataset of the kinetics of a multilayer DNA origami
folding. To this end, we measured the folding kinetics of every staple strand and its two …

Sequence-dependent folding of monolayered DNA origami domains

S Gambietz, LJ Stenke, B Saccà - Nanoscale, 2023 - pubs.rsc.org
Current models of DNA origami folding can explain the yield of the assembly process and
the isomerization of the structure upon the application of mechanical forces. Nevertheless …

Mechanism of DNA origami folding elucidated by mesoscopic simulations

M DeLuca, D Duke, T Ye, M Poirier, Y Ke… - Nature …, 2024 - nature.com
Many experimental and computational efforts have sought to understand DNA origami
folding, but the time and length scales of this process pose significant challenges. Here, we …

Design principles for accurate folding of DNA origami

T Aksel, E J. Navarro, N Fong, SM Douglas - Proceedings of the National …, 2024 - pnas.org
We describe design principles for accurate folding of three-dimensional DNA origami. To
evaluate design rules, we reduced the problem of DNA strand routing to the known problem …

Simulations of DNA-origami self-assembly reveal design-dependent nucleation barriers

A Cumberworth, D Frenkel, A Reinhardt - Nano Letters, 2022 - ACS Publications
Nucleation is the rate-determining step in the kinetics of many self-assembly processes.
However, the importance of nucleation in the kinetics of DNA-origami self-assembly, which …

Models and simulations of structural DNA nanotechnology reveal fundamental principles of self-assembly

A Cumberworth, A Reinhardt - Chemical Society Reviews, 2025 - pubs.rsc.org
DNA is not only a centrally important molecule in biology: the specificity of bonding that
allows it to be the primary information storage medium for life has also allowed it to become …