COVID‐19 and neutrophils: the relationship between hyperinflammation and neutrophil extracellular traps

L Borges, TC Pithon-Curi, R Curi… - Mediators of …, 2020 - Wiley Online Library
Coronavirus disease 2019 (COVID‐19) is a virus‐induced respiratory disease that may
progress to acute respiratory distress syndrome (ARDS) and is triggered by …

Neutrophil‐based drug delivery systems

D Chu, X Dong, X Shi, C Zhang, Z Wang - Advanced materials, 2018 - Wiley Online Library
White blood cells (WBCs) are a major component of immunity in response to pathogen
invasion. Neutrophils are the most abundant WBCs in humans, playing a central role in …

Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients

Y **ong, Y Liu, L Cao, D Wang, M Guo… - Emerging microbes & …, 2020 - Taylor & Francis
Circulating in China and 158 other countries and areas, the ongoing COVID-19 outbreak
has caused devastating mortality and posed a great threat to public health. However, efforts …

Identification of polarized macrophage subsets in zebrafish

M Nguyen-Chi, B Laplace-Builhe, J Travnickova… - Elife, 2015 - elifesciences.org
While the mammalian macrophage phenotypes have been intensively studied in vitro, the
dynamic of their phenotypic polarization has never been investigated in live vertebrates. We …

Inflammation and antiviral immune response associated with severe progression of COVID-19

Q Zhang, Y Meng, K Wang, X Zhang, W Chen… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease-2019 (COVID-19) is a novel respiratory disease induced by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It remains poorly understood how …

Proteomic characteristics of bronchoalveolar lavage fluid in critical COVID‐19 patients

HL Zeng, D Chen, J Yan, Q Yang, QQ Han… - The FEBS …, 2021 - Wiley Online Library
Up to 10–20% of patients with coronavirus disease 2019 (COVID‐19) develop a severe
pulmonary disease due to immune dysfunction and cytokine dysregulation. However, the …

Neutrophil-to-lymphocyte ratio an inflammatory biomarker, and prognostic marker in heart failure, cardiovascular disease and chronic inflammatory diseases: New …

A García-Escobar, S Vera-Vera, D Tébar-Márquez… - Microvascular …, 2023 - Elsevier
In the 20th century, research focused on cholesterol and lipoproteins as the key mechanism
in establishing atherosclerotic cardiovascular disease (ASCVD). Given that some studies …

17β-estradiol protects females against influenza by recruiting neutrophils and increasing virus-specific CD8 T cell responses in the lungs

DP Robinson, OJ Hall, TL Nilles, JH Bream… - Journal of …, 2014 - Am Soc Microbiol
ABSTRACT 17β-Estradiol (E2) treatment limits the pathology associated with pulmonary
diseases caused by pathogens, allergens, and asthma, partly by reducing the production of …

[HTML][HTML] The cell surface mucin MUC1 limits the severity of influenza A virus infection

JL McAuley, L Corcilius, HX Tan, RJ Payne… - Mucosal …, 2017 - Elsevier
Cell surface mucin (cs-mucin) glycoproteins are constitutively expressed at the surface of
respiratory epithelia where pathogens such as influenza A virus (IAV) gain entry into cells …

Evaluation of the Efficacy of a Bacteriophage in the Treatment of Pneumonia Induced by Multidrug Resistance Klebsiella pneumoniae in Mice

F Cao, X Wang, L Wang, Z Li, J Che… - BioMed Research …, 2015 - Wiley Online Library
Multidrug‐resistant Klebsiella pneumoniae (MRKP) has steadily grown beyond antibiotic
control. However, a bacteriophage is considered to be a potential antibiotic alternative for …