Unconventional myosins are multi-potent molecular motors that are assigned important roles
in fundamental cellular processes. Depending on their mechano-enzymatic properties and …

Myosins of class VI (MYO 6) are unique actin‐based motor proteins that move cargo towards
the minus ends of actin filaments. As the sole myosin with this directionality, it is critically …

Accumulating evidence indicates that the alternative splicing program undergoes extensive
changes during cancer development and progression. The RNA-binding protein QKI-5 is …

The actin cytoskeleton is of fundamental importance for numerous cellular processes,
including intracellular transport, cell plasticity, and cell migration. However, functions of …

Myosin VI (MVI) has been found to be overexpressed in ovarian, breast and prostate
cancers. Moreover, it has been shown to play a role in regulating cell proliferation and …

Background: N6-methyladenosine (m6A) RNA methylation is an important epigenetic
modification affecting alternative splicing (AS) patterns of genes to regulate gene …

Clathrin light chains (CLCa and CLCb) are major constituents of clathrin-coated vesicles.
Unique functions for these evolutionary conserved paralogs remain elusive, and their role in …

The intracellular functions of myosin motors requires a number of adaptor molecules, which
control cargo attachment, but also fine‐tune motor activity in time and space. These motor …

The actin cytoskeleton is of fundamental importance for cellular structure and plasticity.
However, abundance and function of filamentous actin in the nucleus are still controversial …

Breast cancer (BC) is one of the most common malignancies occurring in women worldwide,
and its incidence is increasing each year. Accumulating evidence indicated that Myosin VI …