Dry eye disease (DED), keratoconjunctivitis sicca or dysfunctional tear syndrome, is the most
prevalent ophthalmic disease which affects a substantial segment of people worldwide with …

The members of the Management and Therapy Subcommittee undertook an evidence-
based review of current dry eye therapies and management options. Management options …

The members of the Tear Film Subcommittee reviewed the role of the tear film in dry eye
disease (DED). The Subcommittee reviewed biophysical and biochemical aspects of tears …

Abstract The TFOS DEWS II Pathophysiology Subcommittee reviewed the mechanisms
involved in the initiation and perpetuation of dry eye disease. Its central mechanism is …

Dry eye disease (DED) is a highly prevalent and debilitating condition affecting several
hundred million people worldwide. Hyaluronic acid (HA) is a naturally occurring …

Clinicians have more options at their disposal in the treatment of dry eye disease than ever
before, including topical medications and devices. SYNOPSIS In this article, we review …

Hyaluronic acid (HA) is commonly used for treating dry eye syndrome (DES). This meta-
analysis was performed to compare the efficacies of HA-and non-HA-based eye drops …

Here we present a miniaturized analog of a blinking human eye to reverse engineer the
complexity of the interface between the ocular system and the external environment. Our …

Mucins are key actors in tear film quality and tear film stability. Alteration of membrane-
bound mucin expression on corneal and conjunctival epithelial cells and/or gel-forming …

Hyaluronic acid (HA), as one of the main components of the extracellular matrix (ECM),
plays an important role in the process of wound-healing and tissue-repair processes due to …