Previous interest in high-density lipoproteins (HDLs) focused on their possible protective
role in atherosclerotic cardiovascular disease (ASCVD). Evidence from genetic studies and …

High-density lipoproteins comprise roughly 25–30% of the circulating proteins involved in
the transport of lipids in circulation. These particles differ in size and lipid composition …

Aims Emerging evidence suggests that remnant cholesterol (RC) promotes atherosclerotic
cardiovascular disease (ASCVD). We aimed to estimate RC-related risk beyond low-density …

Plasma HDL-cholesterol concentrations correlate negatively with the risk of atherosclerotic
cardiovascular disease (ASCVD). According to a widely cited model, HDL elicits its …

Cardiovascular disease (CVD) is still the leading cause of death globally, and
atherosclerosis is the main pathological basis of CVDs. Low-density lipoprotein cholesterol …

The specific interest concerning HDL cholesterol (HDL-C) is related to its ability to uptake
and return surplus cholesterol from peripheral tissues back to the liver and, therefore, to its …

Cardiovascular diseases predominantly result from atherosclerosis, a natural biological
phenomenon reflecting food intake and energy production in humans. Lipolysis of plasma …

Background: Obesity increases the risk of coronary heart disease, partly due to its strong
association with atherogenic dyslipidemia, characterized by high triglycerides and low high …

While targeting elevated serum levels of low-density lipoprotein cholesterol has been the
mainstay of atherosclerosis prevention and treatment for decades, the evidence regarding …

An obese mouse model induced by high-fat diet (HFD) feeding was used to reveal the role
of piperine in modulating gut microbiota (GM). Piperine was administrated at 20 and 40 …