Genomic data often highlights an inconsistency between the number of gene clusters
identified using bioinformatic approaches as potentially producing secondary metabolites …

Actinobacteria are wide spread in nature and represent the largest taxonomic group within
the domain Bacteria. They are abundant in soil and have been extensively explored for their …

Covering: 2010 up to 2017 Life on Earth is characterized by a remarkable abundance of
symbiotic and highly refined relationships among life forms. Defined as any kind of close …

Microbial symbiotic communities of marine macro-organisms carry functional metabolic
profiles different to the ones found terrestrially and within surrounding marine environments …

Marine sponges harbor diversified bacterial symbionts many of which produce a wide array
of bioactive compounds including antibiotics. The sponge-associated bacteria of Saint …

Microorganisms possess a variety of survival mechanisms, including the production of
antimicrobials that function to kill and/or inhibit the growth of competing microorganisms …

To combat the ineffectiveness of currently available pharmaceutical medications, caused by
the emergence of increasingly resistant bacterial and fungal strains, novel antibacterial and …

Marine sponges have a long history of farming, starting with bath sponges over 5000 years
ago in the Mediterranean. Many species have since been found appropriate for distinct …

Microorganisms are the dominating source of food and nutrition for sponges and play an
important role in sponge structure, chemical defense, excretion and evolution. In recent …

The misuse and overuse of antibiotics have led to the emergence of multidrug-resistant
microorganisms, which decreases the chance of treating those infected with existing …