Quantitative mass spectrometry in proteomics: a critical review
The quantification of differences between two or more physiological states of a biological
system is among the most important but also most challenging technical tasks in proteomics …
system is among the most important but also most challenging technical tasks in proteomics …
Data processing for mass spectrometry-based metabolomics
M Katajamaa, M Orešič - Journal of chromatography A, 2007 - Elsevier
Modern analytical technologies afford comprehensive and quantitative investigation of a
multitude of different metabolites. Typical metabolomic experiments can therefore produce …
multitude of different metabolites. Typical metabolomic experiments can therefore produce …
Chromatographic peak alignment using derivative dynamic time war**
C Bork, K Ng, Y Liu, A Yee… - Biotechnology …, 2013 - Wiley Online Library
Chromatogram overlays are frequently used to monitor inter‐batch performance of
bioprocess purification steps. However, the objective analysis of chromatograms is difficult …
bioprocess purification steps. However, the objective analysis of chromatograms is difficult …
A high-resolution mass spectrometer to measure atmospheric ion composition
In this paper we present recent achievements on develo** and testing a tool to detect the
composition of ambient ions in the mass/charge range up to 2000 Th. The instrument is an …
composition of ambient ions in the mass/charge range up to 2000 Th. The instrument is an …
Proteomics: a pragmatic perspective
The evolution of mass spectrometry–based proteomic technologies has advanced our
understanding of the complex and dynamic nature of proteomes while concurrently …
understanding of the complex and dynamic nature of proteomes while concurrently …
Temporal proteome and lipidome profiles reveal hepatitis C virus-associated reprogramming of hepatocellular metabolism and bioenergetics
DL Diamond, AJ Syder, JM Jacobs… - PLoS …, 2010 - journals.plos.org
Proteomic and lipidomic profiling was performed over a time course of acute hepatitis C
virus (HCV) infection in cultured Huh-7.5 cells to gain new insights into the intracellular …
virus (HCV) infection in cultured Huh-7.5 cells to gain new insights into the intracellular …
Toward an integrated machine learning model of a proteomics experiment
In recent years machine learning has made extensive progress in modeling many aspects of
mass spectrometry data. We brought together proteomics data generators, repository …
mass spectrometry data. We brought together proteomics data generators, repository …
Dengue virus infection perturbs lipid homeostasis in infected mosquito cells
Dengue virus causes∼ 50–100 million infections per year and thus is considered one of the
most aggressive arthropod-borne human pathogen worldwide. During its replication …
most aggressive arthropod-borne human pathogen worldwide. During its replication …
Fragmentation trees reloaded
Background Untargeted metabolomics commonly uses liquid chromatography mass
spectrometry to measure abundances of metabolites; subsequent tandem mass …
spectrometry to measure abundances of metabolites; subsequent tandem mass …
[HTML][HTML] Liquid chromatography mass spectrometry-based proteomics: biological and technological aspects
Mass spectrometry-based proteomics has become the tool of choice for identifying and
quantifying the proteome of an organism. Though recent years have seen a tremendous …
quantifying the proteome of an organism. Though recent years have seen a tremendous …