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The immunology of host defence peptides: beyond antimicrobial activity
REW Hancock, EF Haney, EE Gill - Nature Reviews Immunology, 2016 - nature.com
Host defence peptides (HDPs) are short, cationic amphipathic peptides with diverse
sequences that are produced by various cells and tissues in all complex life forms. HDPs …
sequences that are produced by various cells and tissues in all complex life forms. HDPs …
Defensins: a double-edged sword in host immunity
D Xu, W Lu - Frontiers in immunology, 2020 - frontiersin.org
Defensins are a major family of host defense peptides expressed predominantly in
neutrophils and epithelial cells. Their broad antimicrobial activities and multifaceted …
neutrophils and epithelial cells. Their broad antimicrobial activities and multifaceted …
Antimicrobial peptides as biologic and immunotherapeutic agents against cancer: a comprehensive overview
R Roudi, NL Syn, M Roudbary - Frontiers in immunology, 2017 - frontiersin.org
Antimicrobial peptides (AMPs) are a pervasive and evolutionarily ancient component of
innate host defense which is present in virtually all classes of life. In recent years, evidence …
innate host defense which is present in virtually all classes of life. In recent years, evidence …
Antimicrobial host defence peptides: immunomodulatory functions and translational prospects
AM van der Does, PS Hiemstra… - … Peptides: Basics for …, 2019 - Springer
Cationic host defence peptides (CHDPs), also known as antimicrobial peptides, exhibit a
wide range of activities contributing to immune responses and resolution of infections …
wide range of activities contributing to immune responses and resolution of infections …
Role of defensins in tumor biology
L Adyns, P Proost, S Struyf - International journal of molecular sciences, 2023 - mdpi.com
Defensins have long been considered as merely antimicrobial peptides. Throughout the
years, more immune-related functions have been discovered for both the α-defensin and β …
years, more immune-related functions have been discovered for both the α-defensin and β …
Defensins:“Simple” antimicrobial peptides or broad-spectrum molecules?
M Suarez-Carmona, P Hubert, P Delvenne… - Cytokine & growth factor …, 2015 - Elsevier
Small cationic peptides highly conserved in vertebrates, both α-and β-defensins were
primarily identified as anti-microbial compounds involved in innate immunity. While human α …
primarily identified as anti-microbial compounds involved in innate immunity. While human α …
Human beta defensins and cancer: contradictions and common ground
SK Ghosh, TS McCormick, A Weinberg - Frontiers in Oncology, 2019 - frontiersin.org
Human beta-defensins (hBDs,− 1, 2, 3) are a family of epithelial cell derived antimicrobial
peptides (AMPs) that protect mucosal membranes from microbial challenges. In addition to …
peptides (AMPs) that protect mucosal membranes from microbial challenges. In addition to …
[HTML][HTML] Application value of antimicrobial peptides in gastrointestinal tumors
Q Liu, L Wang, D He, Y Wu, X Liu, Y Yang… - International Journal of …, 2023 - mdpi.com
Gastrointestinal cancer is a common clinical malignant tumor disease that seriously
endangers human health and lacks effective treatment methods. As part of the innate …
endangers human health and lacks effective treatment methods. As part of the innate …
Human β-defensins and their synthetic analogs: Natural defenders and prospective new drugs of oral health
M Chen, Z Hu, J Shi, Z **e - Life sciences, 2024 - Elsevier
As a family of cationic host defense peptides, human β-defensins (HBDs) are ubiquitous in
the oral cavity and are mainly synthesized primarily by epithelial cells, serving as the primary …
the oral cavity and are mainly synthesized primarily by epithelial cells, serving as the primary …
Functions of antimicrobial peptides in vertebrates
E Edilia Avila - Current Protein and Peptide Science, 2017 - benthamdirect.com
Objective: The aim of this review is to examine the multiple activities of antimicrobial
peptides (AMPs) in vertebrates. Content: The largest AMP families are the cathelicidins and …
peptides (AMPs) in vertebrates. Content: The largest AMP families are the cathelicidins and …