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Gut microbiota in colorectal cancer development and therapy
Colorectal cancer (CRC) is one of the commonest cancers globally. A unique aspect of CRC
is its intimate association with the gut microbiota, which forms an essential part of the tumour …
is its intimate association with the gut microbiota, which forms an essential part of the tumour …
Bacteria in cancer initiation, promotion and progression
Cancer cells originate from a series of acquired genetic mutations that can drive their
uncontrolled cell proliferation and immune evasion. Environmental factors, including the …
uncontrolled cell proliferation and immune evasion. Environmental factors, including the …
Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine
The human microbiome influences the efficacy and safety of a wide variety of commonly
prescribed drugs. Designing precision medicine approaches that incorporate microbial …
prescribed drugs. Designing precision medicine approaches that incorporate microbial …
[HTML][HTML] Targeted suppression of human IBD-associated gut microbiota commensals by phage consortia for treatment of intestinal inflammation
Human gut commensals are increasingly suggested to impact non-communicable diseases,
such as inflammatory bowel diseases (IBD), yet their targeted suppression remains a …
such as inflammatory bowel diseases (IBD), yet their targeted suppression remains a …
The gut microbiome as a modulator of healthy ageing
The gut microbiome is a contributory factor in ageing-related health loss and in several non-
communicable diseases in all age groups. Some age-linked and disease-linked …
communicable diseases in all age groups. Some age-linked and disease-linked …
Multi-level analysis of the gut–brain axis shows autism spectrum disorder-associated molecular and microbial profiles
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by
heterogeneous cognitive, behavioral and communication impairments. Disruption of the gut …
heterogeneous cognitive, behavioral and communication impairments. Disruption of the gut …
Microbiome confounders and quantitative profiling challenge predicted microbial targets in colorectal cancer development
Despite substantial progress in cancer microbiome research, recognized confounders and
advances in absolute microbiome quantification remain underused; this raises concerns …
advances in absolute microbiome quantification remain underused; this raises concerns …
Machine learning for microbiologists
Abstract Machine learning is increasingly important in microbiology where it is used for tasks
such as predicting antibiotic resistance and associating human microbiome features with …
such as predicting antibiotic resistance and associating human microbiome features with …
[HTML][HTML] Gut microbiota-derived bile acids in intestinal immunity, inflammation, and tumorigenesis
Inflammatory bowel disease (IBD) and colorectal cancer (CRC) are heterogeneous intestinal
diseases that threaten the health of an increasing number of individuals as their lifestyles …
diseases that threaten the health of an increasing number of individuals as their lifestyles …
Next-generation sequencing: insights to advance clinical investigations of the microbiome
Next-generation sequencing (NGS) technology has advanced our understanding of the
human microbiome by allowing for the discovery and characterization of unculturable …
human microbiome by allowing for the discovery and characterization of unculturable …