The somatostatin-secreting pancreatic δ-cell in health and disease
The somatostatin-secreting δ-cells comprise~ 5% of the cells of the pancreatic islets. The δ-
cells have complex morphology and might interact with many more islet cells than …
cells have complex morphology and might interact with many more islet cells than …
Continuous glucose monitoring and physical activity
O Schubert-Olesen, J Kröger, T Siegmund… - International Journal of …, 2022 - mdpi.com
Continuous glucose monitoring (CGM) use has several potential positive effects on diabetes
management. These benefits are, eg, increased time in range (TIR), optimized therapy, and …
management. These benefits are, eg, increased time in range (TIR), optimized therapy, and …
The benefits and limits of technological advances in glucose management around physical activity in patients type 1 diabetes
Physical activity is highly recommended for patients living with type 1 diabetes (T1D) due to
its varied health benefits. Nevertheless, glucose management, during and in the hours …
its varied health benefits. Nevertheless, glucose management, during and in the hours …
[HTML][HTML] Antagonizing somatostatin receptor subtype 2 and 5 reduces blood glucose in a gut-and GLP-1R–dependent manner
Somatostatin (SS) inhibits glucagon-like peptide-1 (GLP-1) secretion in a paracrine manner.
We hypothesized that blocking somatostatin subtype receptor 2 (SSTR2) and 5 (SSTR5) …
We hypothesized that blocking somatostatin subtype receptor 2 (SSTR2) and 5 (SSTR5) …
Interstitial glucose and physical exercise in type 1 diabetes: integrative physiology, technology, and the gap in-between
Continuous and flash glucose monitoring systems measure interstitial fluid glucose
concentrations within a body compartment that is dramatically altered by posture and is …
concentrations within a body compartment that is dramatically altered by posture and is …
α-cell electrophysiology and the regulation of glucagon secretion
Glucagon is the principal glucose-elevating hormone that forms the first-line defence against
hypoglycaemia. Along with insulin, glucagon also plays a key role in maintaining systemic …
hypoglycaemia. Along with insulin, glucagon also plays a key role in maintaining systemic …
The endocrine pancreas during exercise in people with and without type 1 diabetes: Beyond the beta-cell
O McCarthy, S Schmidt, MB Christensen… - Frontiers in …, 2022 - frontiersin.org
Although important for digestion and metabolism in repose, the healthy endocrine pancreas
also plays a key role in facilitating energy transduction around physical exercise. During …
also plays a key role in facilitating energy transduction around physical exercise. During …
Hyperglycemia but not hyperinsulinemia is favorable for exercise in type 1 diabetes: a pilot study
OBJECTIVE To distinguish the effects of hyperglycemia and hyperinsulinemia on exercise-
induced increases in Rd and endogenous glucose production (EGP) in type 1 diabetes …
induced increases in Rd and endogenous glucose production (EGP) in type 1 diabetes …
Single-hormone artificial pancreas use in diabetes: clinical efficacy and remaining challenges
IN BRIEF Artificial pancreas systems are rapidly develo** and constitute the most
promising technology for insulin-requiring diabetes management. Single-hormone systems …
promising technology for insulin-requiring diabetes management. Single-hormone systems …
Innate Immunity in Type 1 Diabetes
A Tegehall - 2024 - diva-portal.org
Paper I sought to investigate a potential link between insulitis and the innate immune system
using a novel animal model and compare the outcome with type 1 diabetes in humans …
using a novel animal model and compare the outcome with type 1 diabetes in humans …