Wearable and Implantable Biosensors: Mechanisms and Applications for Closed-Loop Therapeutic Systems

Z Zheng, R Zhu, I Peng, Z Xu, Y Jiang - Journal of Materials Chemistry …, 2024 - pubs.rsc.org
This review article examines the current state of wearable and implantable biosensors,
offering an overview of their biosensing mechanisms and applications. We also delve into …

Platinum nanozymes counteract photoreceptor degeneration and retina inflammation in a light-damage model of age-related macular degeneration

S Cupini, S Di Marco, L Boselli, A Cavalli, G Tarricone… - ACS …, 2023 - ACS Publications
Degeneration of photoreceptors in age-related macular degeneration (AMD) is associated
with oxidative stress due to the intense aerobic metabolism of rods and cones that if not …

Targeted drug delivery vehicles mediated by nanocarriers and aptamers for posterior eye disease therapeutics: Barriers, recent advances and potential opportunities

T Zhang, X **, N Zhang, X Jiao, Y Ma, R Liu… - …, 2022 - iopscience.iop.org
Nanomedicine and aptamer have excellent potential in giving play to passive and active
targeting respectively, which are considered to be effective strategies in the retro-ocular drug …

Effects of intravitreal injection of siRNA against caspase-2 on retinal and optic nerve degeneration in air blast induced ocular trauma

CN Thomas, A Bernardo-Colón, E Courtie, G Essex… - Scientific reports, 2021 - nature.com
Ocular repeated air blast injuries occur from low overpressure blast wave exposure, which
are often repeated and in quick succession. We have shown that caspase-2 caused the …

Biomimetic, injectable, and self-healing hydrogels with sustained release of ranibizumab to treat retinal neovascularization

N Duan, L Mei, L Hu, X Yin, X Wei, Y Li… - … Applied Materials & …, 2023 - ACS Publications
Retinal neovascularization (RNV) is a typical feature of ischemic retinal diseases that can
lead to traction retinal detachment and even blindness in patients, in which the vascular …

Advanced nanomedicines for the treatment of age-related macular degeneration

YS Kwon, Z Han - Nanoscale, 2024 - pubs.rsc.org
The critical and unmet medical need for novel therapeutic advancements in the treatment of
age-related macular degeneration (AMD) cannot be overstated, particularly given the aging …

Multiple small floaters associated with silicone oil droplets following intravitreal pegcetacoplan injection

J Bijon, R Mundae, Y Fisher, KB Freund - JAMA ophthalmology, 2023 - jamanetwork.com
Results| Only 8 (15.4%) of the 52 questions submitted initially were graded as completely
accurate. Examples of responses are provided in the Table. After resubmission of the …

Safety of receiving anti–vascular endothelial growth factor intravitreal injection in office-based vs operating room settings: a meta-analysis

T Li, J Sun, J Min, S Zhou, X Zhu, H Jia… - JAMA …, 2021 - jamanetwork.com
Importance Compared with the operating room (OR), office-based intravitreal injection (IVI)
is considered a more cost-effective and convenient approach, yet clinical outcomes of IVIs …

Association between health insurance and primary care vision testing among children and adolescents

OJ Killeen, HJ Choi, NS Kannan, AO Asare… - JAMA …, 2023 - jamanetwork.com
Methods| We pooled data from the 2018 to 2020 National Survey of Children's Health
(NSCH), an annual, nationally representative cross-sectional study. The University of …

Advancements in Nanogels for Enhanced Ocular Drug Delivery: Cutting-Edge Strategies to Overcome Eye Barriers

H Lee, H Noh - Gels, 2023 - mdpi.com
Nanomedicine in gel or particle formation holds considerable potential for enhancing
passive and active targeting within ocular drug delivery systems. The complex barriers of the …