Over the past decade, circular RNAs (circRNAs) have emerged as a large class of primarily
non-coding RNA molecules, many of which have key roles in cancer development and …

Significant progress has been made in circular RNA (circRNA) research in recent years.
Increasing evidence suggests that circRNAs play important roles in many cellular processes …

Epigenetics is closely related to cardiovascular diseases. Genome-wide linkage and
association analyses and candidate gene approaches illustrate the multigenic complexity of …

Cardiovascular diseases (CVDs) remain a leading global cause of morbidity and mortality.
These diseases have a multifaceted nature being influenced by a multitude of biochemical …

Human osteogenic differentiation is a complex and well-orchestrated process which
involves a plethora of molecular players and cellular processes. A growing number of …

Circular RNA (circRNA) is a class of endogenous noncoding RNA (ncRNA), presenting as a
special covalent closed loop without a 5′ cap or 3′ tail, maintaining resistance to RNA …

Osteoporosis is a systemic metabolic disease, mainly characterized by reduced bone
mineral density and destruction of bone tissue microstructure. However, the molecular …

Integrins have been the research focus of cell-extracellular matrix adhesion (ECM) and
cytokine receptor signal transduction. They are involved in the regulation of bone …

Bone healing is a multistage process involving the recruitment of cells, revascularization,
and osteogenic differentiation, all of which are modulated in the temporal sequence to …

In cell transplantation therapy, mesenchymal stem cells (MSCs) are ideal seed cells due to
their easy acquisition and cultivation, strong regenerative capacity, multi-directional …