[HTML][HTML] Friedreich ataxia-pathogenesis and implications for therapies
Friedreich ataxia is the most common of the hereditary ataxias. It is due to homozygous/
compound heterozygous mutations in FXN. This gene encodes frataxin, a protein largely …
compound heterozygous mutations in FXN. This gene encodes frataxin, a protein largely …
A Combined Spectroscopic and In Silico Approach to Evaluate the Interaction of Human Frataxin with Mitochondrial Superoxide Dismutase
D Doni, M Meggiolaro, J Santos, G Audran… - Biomedicines, 2021 - mdpi.com
Frataxin (FXN) is a highly conserved mitochondrial protein whose deficiency causes
Friedreich's ataxia, a neurodegenerative disease. The precise physiological function of FXN …
Friedreich's ataxia, a neurodegenerative disease. The precise physiological function of FXN …
Theoretical and Experimental Elucidation of the Adsorption Process of a Bioinspired Peptide on Mineral Surfaces
Inorganic materials used for biomedical applications such as implants generally induce the
adsorption of proteins on their surface. To control this phenomenon, the bioinspired …
adsorption of proteins on their surface. To control this phenomenon, the bioinspired …
Frataxins emerge as new players of the intracellular antioxidant machinery
AB Uceda, J Donoso, J Frau, B Vilanova, M Adrover - Antioxidants, 2021 - mdpi.com
Frataxin is a mitochondrial protein which deficiency causes Friedreich's ataxia, a cardio-
neurodegenerative disease. The lack of frataxin induces the dysregulation of mitochondrial …
neurodegenerative disease. The lack of frataxin induces the dysregulation of mitochondrial …
DockSurf: A Molecular Modeling Software for the Prediction of Protein/Surface Adhesion
The elucidation of structural interfaces between proteins and inorganic surfaces is a crucial
aspect of bionanotechnology development. Despite its significance, the interfacial structures …
aspect of bionanotechnology development. Despite its significance, the interfacial structures …
Nouvelles stratégies d'inhibition de Chlamydia trachomatis par la synthèse de nano-objets ou de composés organiques
E Adhel - 2023 - theses.hal.science
Ma thèse est une étude pluridisciplinaire axée sur deux stratégies innovantes pour inhiber
Chlamydia trachomatis, une bactérie pathogène. La première est une stratégie en …
Chlamydia trachomatis, une bactérie pathogène. La première est une stratégie en …
[PDF][PDF] DNA Damage Response, oxidative stress and GAA-repeat instability in Friedreich's Ataxia cells: what regulates what?
E Palumbo, MV Miglietta, A Russo - bura.brunel.ac.uk
To address the mechanisms involved in GAA-trinucleotide expansion in Friedreich's Ataxia
(FRDA) families, we are deepening two strictly related issues: 1) whether the GAA …
(FRDA) families, we are deepening two strictly related issues: 1) whether the GAA …
JOINT MEETING AGI–SIMAG
CCS Agostino, V Guelfa - associazionegeneticaitaliana.it
JOINT MEETING AGI – SIMAG Page 1 Congress Programme 12.20-13.10 LECTURE: “Tumors
as wounds that never heal”: insights from YAP/TAZ biology Stefano Piccolo, University of …
as wounds that never heal”: insights from YAP/TAZ biology Stefano Piccolo, University of …
Étude de l'homéostasie du fer dans des modèles cellulaires de l'ataxie de Friedreich et d'autres défauts de synthèse des centres Fe-S
F Petit - 2020 - theses.hal.science
L'ataxie de Friedreich (AF) est une maladie neurodégénérative autosomique récessive se
caractérisant par une ataxie spinocérébelleuse et une cardiomyopathie hypertrophique …
caractérisant par une ataxie spinocérébelleuse et une cardiomyopathie hypertrophique …