• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

The CCL2-CCR2 axis is one of the major chemokine signaling pathways that has received
special attention because of its function in the development and progression of …

Arrhythmogenic cardiomyopathy (ACM) is a heart muscle disease characterized by
prominent “non-ischemic” myocardial scarring predisposing to ventricular electrical …

Nuclear factor κ-B (NFκB) is activated in iPSC-cardiac myocytes from patients with
arrhythmogenic cardiomyopathy (ACM) under basal conditions, and inhibition of NFκB …

Inflammatory activation is increasingly recognized as a nonconventional risk factor for
arrhythmias, and experimental studies provided robust evidence that this association is …

Background Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a familial cardiac
disease associated with ventricular arrhythmias and an increased risk of sudden cardiac …

Background: There is a paucity of data regarding the phenotype of dilated cardiomyopathy
(DCM) gene variants in the general population. We aimed to determine the frequency and …

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a genetic cardiac disease that
leads to ventricular tachycardia (VT), a life-threatening heart rhythm disorder. Treating ARVC …

Arrhythmogenic cardiomyopathy (ACM) is a genetically determined myocardial disease,
characterized by myocytes necrosis with fibrofatty substitution and ventricular arrhythmias …

Myocarditis is clinically characterized by chest pain, arrhythmias, and heart failure, and
treatment is often supportive. Mutations in DSP, a gene encoding the desmosomal protein …