Voltage map** in subcellular nanodomains using electro-diffusion modeling
F Paquin-Lefebvre, D Holcman - The Journal of Chemical Physics, 2024 - pubs.aip.org
Voltage distribution in sub-cellular micro-domains such as neuronal synapses, small
protrusions, or dendritic spines regulates the opening and closing of ionic channels, energy …
protrusions, or dendritic spines regulates the opening and closing of ionic channels, energy …
[BOOK][B] Asymptotics of Elliptic and Parabolic PDEs
D Holcman, Z Schuss - 2018 - Springer
This book is a summary of modern asymptotic methods for the construction of solutions to
boundary value problems for partial differential equations (PDEs) arising from modern …
boundary value problems for partial differential equations (PDEs) arising from modern …
Synaptic cleft geometry modulates NMDAR opening probability by tuning neurotransmitter residence time
Synaptic morphology plays a critical role in modulating the dynamics of neurotransmitter
diffusion and receptor activation in interneuron communication. Central physical aspects of …
diffusion and receptor activation in interneuron communication. Central physical aspects of …
Voltage laws in nanodomains revealed by asymptotics and simulations of electro-diffusion equations
F Paquin-Lefebvre, AB Moreno, D Holcman - arxiv preprint arxiv …, 2024 - arxiv.org
Characterizing the local voltage distribution within nanophysiological domains, driven by
ionic currents through membrane channels, is crucial for studying cellular activity in modern …
ionic currents through membrane channels, is crucial for studying cellular activity in modern …
Steady-state voltage distribution in three-dimensional cusp-shaped funnels modeled by PNP
J Cartailler, D Holcman - Journal of mathematical biology, 2019 - Springer
We study here the bulk electro-diffusion properties of micro-and nanodomains containing a
cusp-shaped structure in three-dimensions when the cation concentration dominates over …
cusp-shaped structure in three-dimensions when the cation concentration dominates over …
Modeling the voltage distribution in a non-locally but globally electroneutral confined electrolyte medium: applications for nanophysiology
A Tricot, IM Sokolov, D Holcman - Journal of Mathematical Biology, 2021 - Springer
The distribution of voltage in sub-micron cellular domains remains poorly understood. In
neurons, the voltage results from the difference in ionic concentrations which are …
neurons, the voltage results from the difference in ionic concentrations which are …
Modeling ionic flow between small targets: insights from diffusion and electro-diffusion theory
F Paquin-Lefebvre, D Holcman - Target Search Problems, 2024 - Springer
The flow of ions through permeable channels causes voltage drop in physiological
nanodomains such as synapses, dendrites and dendritic spines and other protrusions. How …
nanodomains such as synapses, dendrites and dendritic spines and other protrusions. How …
Reply to 'Only negligible deviations from electroneutrality are expected in dendritic spines'
Redefining capacitance In idealized electrolytes as described by Barbour, with equal ionic
concentrations and equal mobility, charges in excess accumulate close to the membrane …
concentrations and equal mobility, charges in excess accumulate close to the membrane …
Systems Isomorphisms in Stochastic Dynamic Systems
R Venkatachalapathy - 2020 - search.proquest.com
The identification of isomorphisms between disparate systems is an important focus of
systems science. Such isomorphisms have not only conceptual and pedagogical value to …
systems science. Such isomorphisms have not only conceptual and pedagogical value to …
Universal Biological Motions for Educational Robot Theatre and Games
Paper presents a concept that is new to robotics education and social robotics. It is based on
theatrical games, in which students create “biological”,“characteristic” and natural motions …
theatrical games, in which students create “biological”,“characteristic” and natural motions …