[HTML][HTML] Skeletal muscle aging: influence of oxidative stress and physical exercise

MJ Gomes, PF Martinez, LU Pagan, RL Damatto… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Skeletal muscle abnormalities are responsible for significant disability in the elderly.
Sarcopenia is the main alteration occurring during senescence and a key public health …

Murine models of heart failure with preserved ejection fraction: a “fishing expedition”

M Valero-Muñoz, W Backman, F Sam - Basic to Translational Science, 2017 - jacc.org
Heart failure with preserved ejection fraction (HFpEF) is characterized by signs and
symptoms of heart failure in the presence of a normal left ventricular ejection fraction …

Myokines and heart failure: challenging role in adverse cardiac remodeling, myopathy, and clinical outcomes

AE Berezin, AA Berezin, M Lichtenauer - Disease Markers, 2021 - Wiley Online Library
Heart failure (HF) is a global medical problem that characterizes poor prognosis and high
economic burden for the health system and family of the HF patients. Although modern …

Mood disorders in the elderly: prevalence, functional impact, and management challenges

LCL Valiengo, F Stella, OV Forlenza - … disease and treatment, 2016 - Taylor & Francis
Despite the lower prevalence of severe mood disorders in the elderly as compared to
younger adults, late-life depression and bipolar disorder (BD) are more strongly associated …

[HTML][HTML] Cardiac cachexia: perspectives for prevention and treatment

MP Okoshi, RV Capalbo, FG Romeiro… - Arquivos brasileiros de …, 2016 - SciELO Brasil
Cachexia is a prevalent pathological condition associated with chronic heart failure. Its
occurrence predicts increased morbidity and mortality independent of important clinical …

Heart failure with preserved ejection fraction: present status and future directions

S Yoon, GH Eom - Experimental & molecular medicine, 2019 - nature.com
The clinical importance of heart failure with preserved ejection fraction (HFpEF) has recently
become apparent. HFpEF refers to heart failure (HF) symptoms with normal or near-normal …

Muscle changes during atrophy

A Dumitru, BM Radu, M Radu, SM Cretoiu - Muscle Atrophy, 2018 - Springer
Muscle atrophy typically is a direct effect of protein degradation induced by a diversity of
pathophysiologic states such as disuse, immobilization, denervation, aging, sepsis …

Effects of aerobic and resistance exercise on cardiac remodelling and skeletal muscle oxidative stress of infarcted rats

MJ Gomes, LU Pagan, ARR Lima… - Journal of cellular …, 2020 - Wiley Online Library
We compared the influence of aerobic and resistance exercise on cardiac remodelling,
physical capacity and skeletal muscle oxidative stress in rats with MI‐induced heart failure …

Influence of apocynin on cardiac remodeling in rats with streptozotocin-induced diabetes mellitus

R Gimenes, C Gimenes, CM Rosa, NP Xavier… - Cardiovascular …, 2018 - Springer
Background Increased reactive oxygen species (ROS) generation in diabetes mellitus (DM)
is an important mechanism leading to diabetic cardiomyopathy. Apocynin, a drug isolated …

Beneficial effects of physical exercise on functional capacity and skeletal muscle oxidative stress in rats with aortic stenosis‐induced heart failure

MJ Gomes, PF Martinez, DHS Campos… - Oxidative medicine …, 2016 - Wiley Online Library
Objective. We evaluated the influence of exercise on functional capacity, cardiac
remodeling, and skeletal muscle oxidative stress, MAPK, and NF‐κB pathway in rats with …