At the beginning of the COVID-19 outbreak (end 2019− 2020), therapeutic treatments based
on approved drugs have been the fastest approaches to combat the new coronavirus …

The emergence of SARS-CoV-2 variants stresses the continued need for broad-spectrum
therapeutic antibodies. Several therapeutic monoclonal antibodies or cocktails have been …

The rapid emergence of SARS-CoV-2 variants of concern (VoC) and the threat of future
zoonotic sarbecovirus spillover emphasizes the need for broadly protective next-generation …

The Receptor Binding Domain (RBD) of SARS-CoV-2, the virus responsible for the COVID-
19 pandemic, is the functional region of the viral Spike protein (S), which is involved in cell …

COVID-19 is a devastating pandemic responsible for the current global health crisis.
Hyperimmune milk, produced after maternal immunisation of bovines, equines, camels …

Despite vaccines are the main strategy to control the ongoing global COVID-19 pandemic,
their effectiveness could not be enough for individuals with immunosuppression. In these …

The emergence and dissemination of the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) and the resulting COVID-19 pandemic triggered a global public health crisis …

Neutralizing antibody-based passive immunotherapy could be an important therapeutic
option against COVID-19. Herein, we demonstrate that equines hyper-immunized with …

The COVID-19 pandemic caused by the severe acute syndrome virus 2 (SARS-CoV-2) has
been around since November 2019. As of early June 2022, more than 527 million cases …

This study aimed to develop an equine-derived hyperimmune serum against SARS-CoV-2
and evaluate its efficacy as a potential immunotherapy tool for the treatment of known and …