Ecology and evolution of Mycobacterium tuberculosis

S Gagneux - Nature Reviews Microbiology, 2018 - nature.com
Tuberculosis (TB) is the number one cause of human death due to an infectious disease.
The causative agents of TB are a group of closely related bacteria known as the …

[HTML][HTML] Consequences of genomic diversity in Mycobacterium tuberculosis

M Coscolla, S Gagneux - Seminars in immunology, 2014 - Elsevier
The causative agent of human tuberculosis, Mycobacterium tuberculosis complex (MTBC),
comprises seven phylogenetically distinct lineages associated with different geographical …

Mycobacterium tuberculosis lineage 4 comprises globally distributed and geographically restricted sublineages

D Stucki, D Brites, L Jeljeli, M Coscolla, Q Liu… - Nature …, 2016 - nature.com
Generalist and specialist species differ in the breadth of their ecological niches. Little is
known about the niche width of obligate human pathogens. Here we analyzed a global …

Phylogenomics of Mycobacterium africanum reveals a new lineage and a complex evolutionary history

M Coscolla, S Gagneux, F Menardo… - Microbial …, 2021 - microbiologyresearch.org
Human tuberculosis (TB) is caused by members of the Mycobacterium tuberculosis complex
(MTBC). The MTBC comprises several human-adapted lineages known as M. tuberculosis …

Co‐evolution of Mycobacterium tuberculosis and Homo sapiens

D Brites, S Gagneux - Immunological reviews, 2015 - Wiley Online Library
The causative agent of human tuberculosis (TB), M ycobacterium tuberculosis, is an obligate
pathogen that evolved to exclusively persist in human populations. For M. tuberculosis to …

Host–pathogen coevolution in human tuberculosis

S Gagneux - … Transactions of the Royal Society B …, 2012 - royalsocietypublishing.org
Tuberculosis (TB) is a disease of antiquity. Yet TB today still causes more adult deaths than
any other single infectious disease. Recent studies show that contrary to the common view …

A New Phylogenetic Framework for the Animal-Adapted Mycobacterium tuberculosis Complex

D Brites, C Loiseau, F Menardo, S Borrell… - Frontiers in …, 2018 - frontiersin.org
Tuberculosis (TB) affects humans and other animals and is caused by bacteria from the
Mycobacterium tuberculosis complex (MTBC). Previous studies have shown that there are at …

Mycobacterium tuberculosis: ecology and evolution of a human bacterium

AL Banuls, A Sanou, NT Van Anh… - Journal of medical …, 2015 - microbiologyresearch.org
Some species of the Mycobacterium tuberculosis complex (MTBC), particularly
Mycobacterium tuberculosis, which causes human tuberculosis (TB), are the first cause of …

The Mechanism for Type I Interferon Induction by Mycobacterium tuberculosis is Bacterial Strain-Dependent

KE Wiens, JD Ernst - PLoS pathogens, 2016 - journals.plos.org
Type I interferons (including IFNαβ) are innate cytokines that may contribute to pathogenesis
during Mycobacterium tuberculosis (Mtb) infection. To induce IFNβ, Mtb must gain access to …

[KNJIGA][B] Tuberculosis in adults and children

M Caws, B Marais, D Heemskerk, J Farrar - 2015 - library.oapen.org
This work contains updated and clinically relevant information about tuberculosis. It is aimed
at providing a succinct overview of history and disease epidemiology, clinical presentation …