The volume of interstitial fluid (ISF) in the human body is three times that of blood. Yet,
collecting diagnostically useful ISF is more challenging than collecting blood because the …

Vascular complications of diabetes pose a severe threat to human health. Prevention and
treatment protocols based on a single vascular complication are no longer suitable for the …

Type 2 Diabetes Mellitus (T2DM), one of the most common metabolic disorders, is caused
by a combination of two primary factors: defective insulin secretion by pancreatic β-cells and …

Understanding gene function and regulation in homeostasis and disease requires
knowledge of the cellular and tissue contexts in which genes are expressed. Here, we …

Although aging has traditionally been viewed as the most important risk factor for
osteoarthritis (OA), an increasing amount of epidemiological evidence has highlighted the …

Cardiovascular diseases create an important burden on the public health systems,
especially in the elderly, mostly because this group of patients frequently suffer from multiple …

Prediabetes is a state of elevated plasma glucose in which the threshold for diabetes has
not yet been reached and can predispose to the development of type 2 diabetes and …

The incidence and prevalence of diabetes mellitus is rapidly increasing worldwide at an
alarming rate. Type 2 diabetes mellitus (T2DM) is the most prevalent form of diabetes …

Background People with type 1 diabetes are at elevated risk of mortality and cardiovascular
disease, yet current guidelines do not consider age of onset as an important risk stratifier …

Background: Type 2 diabetes mellitus (T2DM) has emerged as a pandemic. It has different
complications, both microvascular and macrovascular. Objective: The purpose of this review …