Ligand-induced folding of a two-component signaling receiver domain

VJ Ocasio, F Corrêa, KH Gardner - Biochemistry, 2015 - ACS Publications
To survive and adapt to environmental changes, bacteria commonly use two-component
signaling systems. Minimally, these pathways use histidine kinases (HKs) to detect …

Nuclear Magnetic Resonance Structure and Dynamics of the Response Regulator Sma0114 from Sinorhizobium meliloti

SR Sheftic, PP Garcia, E White, VL Robinson… - Biochemistry, 2012 - ACS Publications
Receiver domains control intracellular responses triggered by signal transduction in
bacterial two-component systems. Here, we report the solution nuclear magnetic resonance …

NMR structure of the HWE kinase associated response regulator Sma0114 in its activated state

SR Sheftic, E White, DJ Gage, AT Alexandrescu - Biochemistry, 2014 - ACS Publications
Bacterial receiver domains modulate intracellular responses to external stimuli in two-
component systems. Sma0114 is the first structurally characterized representative from the …

Role of the PFXFATG [G/Y] motif in the activation of SdrG, a response regulator involved in the alphaproteobacterial general stress response

S Campagne, S Dintner, L Gottschlich, M Thibault… - Structure, 2016 - cell.com
Two-component systems are major signal transduction pathways, which consist of histidine
kinases and response regulators that communicate through phosphorylation. Here, we …

Biophysical and Biochemical Characterization of a REC Domain: Unfolded to Folded Transition of EL_LovR

VJ Ocasio - 2014 - utswmed-ir.tdl.org
Prokaryotes frequently use two component systems to couple environmental stimuli to
adaptive responses. These pathways use histidine kinases to detect environmental cues …

Biochemical and structural characterisation of a two-component signalling system downstream of bacteriophytochrome photoreceptor 1 in Rhizobium NT-26

M Wojnowska - 2013 - discovery.ucl.ac.uk
Prokaryotic signal transduction frequently involves two-component systems (TCSs), typically
comprising a sensor histidine kinase (HK) and a response regulator (RR). Via a conserved …