Tip of the trichome: evolution of acylsugar metabolic diversity in Solanaceae

P Fan, BJ Leong, RL Last - Current Opinion in Plant Biology, 2019 - Elsevier
Highlights•Solanaceae glandular trichomes produce structurally diverse insecticidal
acylsugars.•Diversity is achieved by enzyme promiscuity and core metabolic enzyme …

Non-volatile natural products in plant glandular trichomes: chemistry, biological activities and biosynthesis

Y Liu, SX **g, SH Luo, SH Li - Natural product reports, 2019 - pubs.rsc.org
Covering: 1960s to end of August 2018 Plant glandular trichomes (GTs) are adaptive
structures that are well known as “phytochemical factories” due to their impressive capacity …

Multi-omics of tomato glandular trichomes reveals distinct features of central carbon metabolism supporting high productivity of specialized metabolites

GU Balcke, S Bennewitz, N Bergau, B Athmer… - The Plant …, 2017 - academic.oup.com
Glandular trichomes are metabolic cell factories with the capacity to produce large quantities
of secondary metabolites. Little is known about the connection between central carbon …

Evolutionary routes to biochemical innovation revealed by integrative analysis of a plant-defense related specialized metabolic pathway

GD Moghe, BJ Leong, SM Hurney, A Daniel Jones… - Elife, 2017 - elifesciences.org
The diversity of life on Earth is a result of continual innovations in molecular networks
influencing morphology and physiology. Plant specialized metabolism produces hundreds …

O-Acyl Sugars Protect a Wild Tobacco from Both Native Fungal Pathogens and a Specialist Herbivore

VT Luu, A Weinhold, C Ullah, S Dressel… - Plant …, 2017 - academic.oup.com
Abstract O-Acyl sugars (O-AS) are abundant trichome-specific metabolites that function as
indirect defenses against herbivores of the wild tobacco Nicotiana attenuata; whether they …

Functionally Divergent Alleles and Duplicated Loci Encoding an Acyltransferase Contribute to Acylsugar Metabolite Diversity in Solanum Trichomes

AL Schilmiller, GD Moghe, P Fan, B Ghosh… - The Plant …, 2015 - academic.oup.com
Glandular trichomes from tomato (Solanum lycopersicum) and other species in the
Solanaceae produce and secrete a mixture of O-acylsugars (aliphatic esters of sucrose and …

Acylsugars protect Nicotiana benthamiana against insect herbivory and desiccation

H Feng, L Acosta-Gamboa, LH Kruse, JD Tracy… - Plant Molecular …, 2021 - Springer
Key message Nicotiana benthamiana acylsugar acyltransferase (ASAT) is required for
protection against desiccation and insect herbivory. Knockout mutations provide a new …

In vitro reconstruction and analysis of evolutionary variation of the tomato acylsucrose metabolic network

P Fan, AM Miller, AL Schilmiller, X Liu, I Ofner… - Proceedings of the …, 2016 - pnas.org
Plant glandular secreting trichomes are epidermal protuberances that produce structurally
diverse specialized metabolites, including medically important compounds. Trichomes of …

Single-cell metabolite profiling of stalk and glandular cells of intact trichomes with internal electrode capillary pressure probe electrospray ionization mass …

T Nakashima, H Wada, S Morita… - Analytical …, 2016 - ACS Publications
In this report, we developed the pressure probe electrospray ionization-mass spectrometry
with internal electrode capillary (IEC-PPESI-MS) which enables high spatial-resolution cell …

A feedback-insensitive isopropylmalate synthase affects acylsugar composition in cultivated and wild tomato

J Ning, GD Moghe, B Leong, J Kim, I Ofner… - Plant …, 2015 - academic.oup.com
Acylsugars are insecticidal specialized metabolites produced in the glandular trichomes of
plants in the Solanaceae family. In the tomato clade of the Solanum genus, acylsugars …