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Childhood acute lymphoblastic leukemia: progress through collaboration
Purpose To review the impact of collaborative studies on advances in the biology and
treatment of acute lymphoblastic leukemia (ALL) in children and adolescents. Methods A …
treatment of acute lymphoblastic leukemia (ALL) in children and adolescents. Methods A …
Treatment and biology of pediatric acute lymphoblastic leukemia
M Kato, A Manabe - Pediatrics International, 2018 - Wiley Online Library
Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy. In the past
ALL was intractable but now the survival probability is as high as 80–90%. Improved …
ALL was intractable but now the survival probability is as high as 80–90%. Improved …
Children's Oncology Group Trial AALL1231: a phase III clinical trial testing bortezomib in newly diagnosed T-cell acute lymphoblastic leukemia and lymphoma
PURPOSE To improve the outcomes of patients with T-cell acute lymphoblastic leukemia (T-
ALL) and lymphoblastic lymphoma (T-LL), the proteasome inhibitor bortezomib was …
ALL) and lymphoblastic lymphoma (T-LL), the proteasome inhibitor bortezomib was …
Phase I/phase II study of blinatumomab in pediatric patients with relapsed/refractory acute lymphoblastic leukemia
Purpose Blinatumomab is a bispecific T-cell engager antibody construct targeting CD19 on
B-cell lymphoblasts. We evaluated the safety, pharmacokinetics, recommended dosage, and …
B-cell lymphoblasts. We evaluated the safety, pharmacokinetics, recommended dosage, and …
Pediatric acute lymphoblastic leukemia, version 2.2020, NCCN clinical practice guidelines in oncology
Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy.
Advancements in technology that enhance our understanding of the biology of the disease …
Advancements in technology that enhance our understanding of the biology of the disease …
Dexamethasone and high-dose methotrexate improve outcome for children and young adults with high-risk B-acute lymphoblastic leukemia: a report from Children's …
Purpose Survival for children and young adults with high-risk B-acute lymphoblastic
leukemia has improved significantly, but 20% to 25% of patients are not cured. Children's …
leukemia has improved significantly, but 20% to 25% of patients are not cured. Children's …
Improved survival for children and adolescents with acute lymphoblastic leukemia between 1990 and 2005: a report from the children's oncology group
Purpose To examine population-based improvements in survival and the impact of clinical
covariates on outcome among children and adolescents with acute lymphoblastic leukemia …
covariates on outcome among children and adolescents with acute lymphoblastic leukemia …
Dasatinib plus intensive chemotherapy in children, adolescents, and young adults with philadelphia chromosome–positive acute lymphoblastic leukemia: Results of …
Purpose Addition of imatinib to intensive chemotherapy improved survival for children and
young adults with Philadelphia chromosome–positive acute lymphoblastic leukemia …
young adults with Philadelphia chromosome–positive acute lymphoblastic leukemia …
Pediatric acute lymphoblastic leukemia: where are we going and how do we get there?
Improved supportive care, more precise risk stratification, and personalized chemotherapy
based on the characteristics of leukemic cells and hosts (eg, pharmacokinetics and …
based on the characteristics of leukemic cells and hosts (eg, pharmacokinetics and …
A 50-year journey to cure childhood acute lymphoblastic leukemia
The 50th anniversary of Seminars in Hematology coincides with the 50th anniversary of St.
Jude Children's Research Hospital, and both milestones are inexorably linked to studies …
Jude Children's Research Hospital, and both milestones are inexorably linked to studies …