[HTML][HTML] Advanced gene therapy system for the treatment of solid tumour: A review

Y Ma, J Liao, H Cheng, Q Yang, H Yang - Materials Today Bio, 2024 - Elsevier
In contrast to conventional therapies that require repeated dosing, gene therapy can treat
diseases by correcting defective genes after a single transfection and achieving cascade …

Solid lipid nanoparticle carrier platform containing synthetic TLR4 agonist mediates non-viral DNA vaccine delivery

JE Francis, I Skakic, C Dekiwadia, R Shukla, AC Taki… - Vaccines, 2020 - mdpi.com
There is a growing demand for better delivery systems to improve the stability and efficacy of
DNA vaccines. Here we report the synthesis of a non-viral DNA vaccine delivery system …

Plasmid DNA‐Based Bioluminescence‐Activated System for Photodynamic Therapy in Cancer Treatment

D Fan, T Wang, J Hu, L Zhou, J Zhou, S Wei - ChemMedChem, 2021 - Wiley Online Library
The low depth of tissue penetration by therapeutic light sources severely restricts
photodynamic therapy (PDT) in treating deep‐seated tumors. Using a luciferase/d‐luciferin …

It is all in the delivery: How to augment the efficiency of DNA vaccination

JE Francis, PM Smooker - Advanced Vaccination Technologies for …, 2024 - Elsevier
Nucleic acid vaccines (DNA and RNA) have been the subject of investigation for more than
30 years. The recent successes of mRNA vaccines against COVID-19 disease have …

[引用][C] The Investigation of Adjuvanted Solid Lipid Nanoparticles as a Novel DNA Vaccine Delivery System Against Helicobacter Pylori

JE Francis - 2021 - RMIT University