Endometriosis: recent advances that could accelerate diagnosis and improve care

MJ Griffiths, AW Horne, DA Gibson, N Roberts… - Trends in Molecular …, 2024 - cell.com
Endometriosis is a common disorder associated with pain, gastrointestinal and urinary
symptoms, infertility, and fatigue. It is defined by the presence of endometrial-like lesions …

Neuroendocrine and neuroimmune mechanisms underlying comorbidity of pain and obesity

DH Zhang, YH Fan, YQ Zhang, H Cao - Life Sciences, 2023 - Elsevier
Pain and obesity, as well as their associated impairments, are major health concerns.
Understanding the relationship between the two is the focus of a growing body of research …

[HTML][HTML] Hormonal contraceptive use is associated with differences in women's inflammatory and psychological reactivity to an acute social stressor

S Mengelkoch, J Gassen, GM Slavich, SE Hill - Brain, Behavior, and …, 2024 - Elsevier
Women using hormonal contraceptives (HCs) exhibit numerous signs of chronic
inflammation, including elevated C-reactive protein levels and greater risk of develo** …

Degenerative Cervical Myelopathy induces sex-specific dysbiosis in mice

C Farkas, E Retamal-Fredes, A Ávila… - Frontiers in …, 2023 - frontiersin.org
Degenerative Cervical Myelopathy (DCM) is the most common cause of spinal cord
impairment in elderly populations. It describes a spectrum of disorders that cause …

[HTML][HTML] Sex differences in mechanisms of pain hypersensitivity

JS Mogil, M Parisien, SJ Esfahani… - … & Biobehavioral Reviews, 2024 - Elsevier
The introduction of sex-as-a-biological-variable policies at funding agencies around the
world has led to an explosion of very recent observations of sex differences in the biology …

Gut microbiota in symptomatic uncomplicated diverticular disease stratifies by severity of abdominal pain

A Tursi, S Turroni, R De Bastiani… - European Journal of …, 2025 - journals.lww.com
Objective Patients with symptomatic uncomplicated diverticular disease (SUDD) may have a
disrupted gut microbiota. However, current data are from small sample studies, and reported …

Genetic analysis confirms a link between gastrointestinal disorders and endometriosis

PTK Saunders, AW Horne - Cell Reports Medicine, 2023 - cell.com
Patients with endometriosis often report gastrointestinal symptoms in addition to those
usually considered hallmarks of the disorder (pain and infertility). Yang et al. 1 identify …

[HTML][HTML] A developmental framework for understanding the influence of sex and gender on health: Pediatric pain as an exemplar

KE Boerner, E Keogh, AM Inkster… - Neuroscience & …, 2024 - Elsevier
Sex differences are a robust finding in many areas of adult health, including cardiovascular
disease, psychiatric disorders, and chronic pain. However, many sex differences are not …

An altered gut microbiome in pre-eclampsia: cause or consequence

C Deady, FP McCarthy, A Barron… - Frontiers in Cellular …, 2024 - frontiersin.org
Hypertensive disorders of pregnancy, including pre-eclampsia, are a leading cause of
serious and debilitating complications that affect both the mother and the fetus. Despite the …

[HTML][HTML] A dietary intervention for postmenopausal hot flashes: A potential role of gut microbiome. An exploratory analysis

H Kahleova, DN Holtz, N Strom, A La Reau… - … therapies in medicine, 2023 - Elsevier
Objective This study examined the role of gut microbiome changes in mediating the effects
of a dietary intervention on the frequency and severity of postmenopausal vasomotor …