Concepts of artificial intelligence for computer-assisted drug discovery

X Yang, Y Wang, R Byrne, G Schneider… - Chemical …, 2019 - ACS Publications
Artificial intelligence (AI), and, in particular, deep learning as a subcategory of AI, provides
opportunities for the discovery and development of innovative drugs. Various machine …

Artificial intelligence and machine learning in pathology: the present landscape of supervised methods

HH Rashidi, NK Tran, EV Betts… - Academic …, 2019 - journals.sagepub.com
Increased interest in the opportunities provided by artificial intelligence and machine
learning has spawned a new field of health-care research. The new tools under …

Applications of artificial intelligence and machine learning algorithms to crystallization

C **ouras, F Cameli, GL Quillo… - Chemical …, 2022 - ACS Publications
Artificial intelligence and specifically machine learning applications are nowadays used in a
variety of scientific applications and cutting-edge technologies, where they have a …

Improving protein-protein interactions prediction accuracy using XGBoost feature selection and stacked ensemble classifier

C Chen, Q Zhang, B Yu, Z Yu, PJ Lawrence… - Computers in biology …, 2020 - Elsevier
Protein-protein interactions (PPIs) are involved with most cellular activities at the proteomic
level, making the study of PPIs necessary to comprehending any biological process …

Machine-learning approaches in drug discovery: methods and applications

A Lavecchia - Drug discovery today, 2015 - Elsevier
Highlights•We review machine learning methods/tools relevant to ligand-based virtual
screening.•Machine learning methods classify compounds and predict new active …

LightGBM-PPI: Predicting protein-protein interactions through LightGBM with multi-information fusion

C Chen, Q Zhang, Q Ma, B Yu - Chemometrics and Intelligent Laboratory …, 2019 - Elsevier
Protein-protein interactions (PPIs) play an important role in cell life activities such as
transcriptional regulation, signal transduction and drug signal transduction. The study of …

Taking the leap between analytical chemistry and artificial intelligence: A tutorial review

LB Ayres, FJV Gomez, JR Linton, MF Silva… - Analytica Chimica …, 2021 - Elsevier
The last 10 years have witnessed the growth of artificial intelligence into different research
areas, emerging as a vibrant discipline with the capacity to process large amounts of …

Machine learning methods in chemoinformatics

JBO Mitchell - Wiley Interdisciplinary Reviews: Computational …, 2014 - Wiley Online Library
Machine learning algorithms are generally developed in computer science or adjacent
disciplines and find their way into chemical modeling by a process of diffusion. Though …

Recent advances in machine-learning-based chemoinformatics: a comprehensive review

SK Niazi, Z Mariam - International Journal of Molecular Sciences, 2023 - mdpi.com
In modern drug discovery, the combination of chemoinformatics and quantitative structure–
activity relationship (QSAR) modeling has emerged as a formidable alliance, enabling …

Computer-aided drug design and drug discovery: a prospective analysis

SK Niazi, Z Mariam - Pharmaceuticals, 2023 - mdpi.com
In the dynamic landscape of drug discovery, Computer-Aided Drug Design (CADD) emerges
as a transformative force, bridging the realms of biology and technology. This paper …