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Adenoviral vector-based vaccine platform for COVID-19: Current status
The coronavirus disease (COVID-19) breakout had an unimaginable worldwide effect in the
21st century, claiming millions of lives and putting a huge burden on the global economy …
21st century, claiming millions of lives and putting a huge burden on the global economy …
Rabies–epidemiology, pathogenesis, public health concerns and advances in diagnosis and control: a comprehensive review
Rabies is a zoonotic, fatal and progressive neurological infection caused by rabies virus of
the genus Lyssavirus and family Rhabdoviridae. It affects all warm-blooded animals and the …
the genus Lyssavirus and family Rhabdoviridae. It affects all warm-blooded animals and the …
[HTML][HTML] Adenoviruses as vaccine vectors
N Tatsis, HCJ Ertl - Molecular Therapy, 2004 - cell.com
Adenoviruses have transitioned from tools for gene replacement therapy to bona fide
vaccine delivery vehicles. They are attractive vaccine vectors as they induce both innate and …
vaccine delivery vehicles. They are attractive vaccine vectors as they induce both innate and …
Pre-existing immunity against Ad vectors: humoral, cellular, and innate response, what's important?
H Fausther-Bovendo, GP Kobinger - Human vaccines & …, 2014 - Taylor & Francis
Pre-existing immunity against human adenovirus (HAd) serotype 5 derived vector in the
human population is widespread, thus hampering its clinical use. Various components of the …
human population is widespread, thus hampering its clinical use. Various components of the …
Adenovirus vectors: excellent tools for vaccine development
J Chang - Immune network, 2021 - pmc.ncbi.nlm.nih.gov
Adenovirus was originally used as a vector for gene therapy. In recent years, with the
development of the next-generation vectors with increased safety and high immunogenicity …
development of the next-generation vectors with increased safety and high immunogenicity …
Oral vaccines: a better future of immunization
KWY Kwong, Y **n, NCY Lai, JCC Sung, KC Wu… - Vaccines, 2023 - mdpi.com
Oral vaccines are gaining more attention due to their ease of administration, lower
invasiveness, generally greater safety, and lower cost than injectable vaccines. This review …
invasiveness, generally greater safety, and lower cost than injectable vaccines. This review …
Vaccine and therapeutic options to control chikungunya virus
AM Powers - Clinical microbiology reviews, 2018 - journals.asm.org
Beginning in 2004, chikungunya virus (CHIKV) went from an endemic pathogen limited to
Africa and Asia that caused periodic outbreaks to a global pathogen. Given that outbreaks …
Africa and Asia that caused periodic outbreaks to a global pathogen. Given that outbreaks …
Reprogrammed viruses as cancer therapeutics: targeted, armed and shielded
R Cattaneo, T Miest, EV Shashkova… - Nature Reviews …, 2008 - nature.com
Virotherapy is currently undergoing a renaissance, based on our improved understanding of
virus biology and genetics and our better knowledge of many different types of cancer …
virus biology and genetics and our better knowledge of many different types of cancer …
Combining photothermal therapy and immunotherapy against melanoma by polydopamine-coated Al2O3 nanoparticles
W Chen, M Qin, X Chen, Q Wang, Z Zhang… - Theranostics, 2018 - pmc.ncbi.nlm.nih.gov
Photothermal therapy (PTT) can be an effective antitumor therapy, but it may not completely
eliminate tumor cells, leading to the risk of recurrence or metastasis. Here we describe …
eliminate tumor cells, leading to the risk of recurrence or metastasis. Here we describe …
New insights on adenovirus as vaccine vectors
MO Lasaro, HCJ Ertl - Molecular Therapy, 2009 - cell.com
Adenovirus (Ad) vectors were initially developed for treatment of genetic diseases. Their
usefulness for permanent gene replacement was limited by their high immunogenicity …
usefulness for permanent gene replacement was limited by their high immunogenicity …