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Revisiting the adipocyte: a model for integration of cytokine signaling in the regulation of energy metabolism
Adipose tissue constitutes an extremely active endocrine organ with a network of signaling
pathways enabling the organism to adapt to a wide range of different metabolic challenges …
pathways enabling the organism to adapt to a wide range of different metabolic challenges …
[HTML][HTML] The multifaceted role of aquaporin-9 in health and its potential as a clinical biomarker
Aquaporins (AQPs) are transmembrane channels essential for water, energy, and redox
homeostasis, with proven involvement in a variety of pathophysiological conditions such as …
homeostasis, with proven involvement in a variety of pathophysiological conditions such as …
[HTML][HTML] Aquaporins in insulin resistance and diabetes: More than channels!
Aquaporins (AQPs) are part of the family of the integral membrane proteins. Their function is
dedicated to the transport of water, glycerol, ammonia, urea, H 2 O 2, and other small …
dedicated to the transport of water, glycerol, ammonia, urea, H 2 O 2, and other small …
Aquaglyceroporins: implications in adipose biology and obesity
Aquaporins (AQPs) are membrane water/glycerol channels that are involved in many
physiological processes. Their primary function is to facilitate the bidirectional transfer of …
physiological processes. Their primary function is to facilitate the bidirectional transfer of …
Aquaglyceroporins: drug targets for metabolic diseases?
Aquaporins (AQPs) are a family of transmembrane channel proteins facilitating the transport
of water, small solutes, and gasses across biological membranes. AQPs are expressed in all …
of water, small solutes, and gasses across biological membranes. AQPs are expressed in all …
Reduced hepatic aquaporin-9 and glycerol permeability are related to insulin resistance in non-alcoholic fatty liver disease
Results: AQP9 was the most abundantly (P< 0.0001) expressed aquaglyceroporin in human
liver (AQP9>>> AQP3> AQP7> AQP10). Obese patients with T2D showed increased plasma …
liver (AQP9>>> AQP3> AQP7> AQP10). Obese patients with T2D showed increased plasma …
Leptin administration restores the altered adipose and hepatic expression of aquaglyceroporins improving the non-alcoholic fatty liver of ob/ob mice
Glycerol is an important metabolite for the control of lipid accumulation in white adipose
tissue (WAT) and liver. We aimed to investigate whether exogenous administration of leptin …
tissue (WAT) and liver. We aimed to investigate whether exogenous administration of leptin …
[کتاب][B] Aquaporins in health and disease: new molecular targets for drug discovery
Since the discovery of Aquaporin-1 (AQP1) as a water channel, many studies have revealed
the importance of aquaporins in mammalian physiology and pathophysiology as well as …
the importance of aquaporins in mammalian physiology and pathophysiology as well as …
Aquaporin-9 is involved in the lipid-lowering activity of the nutraceutical silybin on hepatocytes through modulation of autophagy and lipid droplets composition
Hepatic steatosis is the hallmark of non-alcoholic fatty liver disease (NAFLD), the hepatic
manifestation of the metabolic syndrome and insulin resistance with potential evolution …
manifestation of the metabolic syndrome and insulin resistance with potential evolution …
Nonalcoholic fatty liver disease, male sexual dysfunction, and infertility: common links, common problems
DJ Hawksworth, AL Burnett - Sexual Medicine Reviews, 2020 - academic.oup.com
Introduction Nonalcoholic fatty liver disease (NAFLD) is considered a hallmark of metabolic
syndrome (MetS) and a significant contributor to cardiovascular disease (CVD). With the …
syndrome (MetS) and a significant contributor to cardiovascular disease (CVD). With the …