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Arterial stiffness and cardiovascular risk in hypertension
P Boutouyrie, P Chowienczyk, JD Humphrey… - Circulation …, 2021 - ahajournals.org
Arterial stiffness, a leading marker of risk in hypertension, can be measured at material or
structural levels, with the latter combining effects of the geometry and composition of the …
structural levels, with the latter combining effects of the geometry and composition of the …
Vascular smooth muscle cells and arterial stiffening: relevance in development, aging, and disease
The cushioning function of large arteries encompasses distension during systole and recoil
during diastole which transforms pulsatile flow into a steady flow in the microcirculation …
during diastole which transforms pulsatile flow into a steady flow in the microcirculation …
Oxidative stress, inflammation, and vascular aging in hypertension
Guzik and Touyz Oxidation and Inflammation in Vascular Aging 661 and endothelium. 22
Perivascular fibrosis is greatly dependent on immune cells because it is prevented in …
Perivascular fibrosis is greatly dependent on immune cells because it is prevented in …
Sex differences in mechanisms of arterial stiffness
JJ DuPont, RM Kenney, AR Patel… - British journal of …, 2019 - Wiley Online Library
Arterial stiffness progressively increases with aging and is an independent predictor of
cardiovascular disease (CVD) risk. Evidence supports that there are sex differences in the …
cardiovascular disease (CVD) risk. Evidence supports that there are sex differences in the …
Arterial stiffness as a risk factor for clinical hypertension
ME Safar - Nature Reviews Cardiology, 2018 - nature.com
In patients with uncomplicated essential hypertension, cardiac output remains within normal
ranges and intravascular volume is normal or low, assuming the presence of a sufficient …
ranges and intravascular volume is normal or low, assuming the presence of a sufficient …
The role of vascular smooth muscle cells in arterial remodeling: focus on calcification-related processes
Arterial remodeling refers to the structural and functional changes of the vessel wall that
occur in response to disease, injury, or aging. Vascular smooth muscle cells (VSMC) play a …
occur in response to disease, injury, or aging. Vascular smooth muscle cells (VSMC) play a …
Vascular smooth muscle remodeling in conductive and resistance arteries in hypertension
IAM Brown, L Diederich, ME Good… - … , and vascular biology, 2018 - ahajournals.org
Cardiovascular disease is a leading cause of death worldwide and accounts for> 17.3
million deaths per year, with an estimated increase in incidence to 23.6 million by 2030 …
million deaths per year, with an estimated increase in incidence to 23.6 million by 2030 …
Vascular stiffness in aging and disease
SF Vatner, J Zhang, C Vyzas, K Mishra… - Frontiers in …, 2021 - frontiersin.org
The goal of this review is to provide further understanding of increased vascular stiffness
with aging, and how it contributes to the adverse effects of major human diseases …
with aging, and how it contributes to the adverse effects of major human diseases …
Smooth muscle cell and arterial aging: basic and clinical aspects
Arterial aging engages a plethora of key signalling pathways that act in concert to induce
vascular smooth muscle cell (VSMC) phenotypic changes leading to vascular degeneration …
vascular smooth muscle cell (VSMC) phenotypic changes leading to vascular degeneration …
Role of renin-angiotensin-aldosterone system activation in promoting cardiovascular fibrosis and stiffness
538 Hypertension September 2018 or near normal LV ejection fractions, consistent with the
clinical picture of HFpEF. In the I-PRESERVE study (Irbesartan in Heart Failure With …
clinical picture of HFpEF. In the I-PRESERVE study (Irbesartan in Heart Failure With …