The kisspeptin-GnRH pathway in human reproductive health and disease

K Skorupskaite, JT George… - Human reproduction …, 2014‏ - academic.oup.com
BACKGROUND The discovery of kisspeptin as key central regulator of GnRH secretion has
led to a new level of understanding of the neuroendocrine regulation of human reproduction …

Kisspeptins and reproduction: physiological roles and regulatory mechanisms

L Pinilla, E Aguilar, C Dieguez, RP Millar… - Physiological …, 2012‏ - journals.physiology.org
Procreation is essential for survival of species. Not surprisingly, complex neuronal networks
have evolved to mediate the diverse internal and external environmental inputs that regulate …

Central regulation of PCOS: abnormal neuronal-reproductive-metabolic circuits in PCOS pathophysiology

B Liao, J Qiao, Y Pang - Frontiers in endocrinology, 2021‏ - frontiersin.org
Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disease. PCOS
patients are characterized by hyperandrogenemia, anovulation, and metabolic dysfunction …

Sha** of the female human brain by sex hormones: a review

E Rehbein, J Hornung, I Sundström Poromaa… - …, 2021‏ - karger.com
Traditionally sex hormones have been associated with reproductive and developmental
processes only. Since the 1950s we know that hormones can have organizational effects on …

[كتاب][B] Essential reproduction

MH Johnson - 2018‏ - books.google.com
Essential Reproduction provides an accessible account of the fundamentals of reproduction
within the context of cutting-edge knowledge and examples of its application. The eighth …

Kisspeptin/GPR54 system: what do we know about its role in human reproduction?

CM Trevisan, E Montagna, R De Oliveira… - Cellular Physiology and …, 2018‏ - karger.com
Kisspeptin is involved in the control of human reproduction bridging the gap between the
sex steroid levels and feedback mechanisms that control the gonadotropin releasing …

[HTML][HTML] Physiology of GNRH and gonadotropin secretion

P Marques, K Skorupskaite, KS Rozario… - Endotext …, 2022‏ - ncbi.nlm.nih.gov
Gonadotropin hormone-releasing hormone (GnRH) is the key regulator of the reproductive
axis. Its pulsatile secretion determines the pattern of secretion of the gonadotropins follicle …

The emerging therapeutic potential of kisspeptin and neurokinin B

B Patel, K Koysombat, EG Mills, J Tsoutsouki… - Endocrine …, 2024‏ - academic.oup.com
Kisspeptin (KP) and neurokinin B (NKB) are neuropeptides that govern the reproductive
endocrine axis through regulating hypothalamic gonadotropin-releasing hormone (GnRH) …

Comprehensive review on kisspeptin and its role in reproductive disorders

H Clarke, WS Dhillo… - Endocrinology and …, 2015‏ - synapse.koreamed.org
Kisspeptin has recently emerged as a key regulator of the mammalian reproductive axis. It is
known that kisspeptin, acting centrally via the kisspeptin receptor, stimulates secretion of …

Novel Concepts for Inducing Final Oocyte Maturation in In Vitro Fertilization Treatment

A Abbara, SA Clarke, WS Dhillo - Endocrine reviews, 2018‏ - academic.oup.com
Infertility affects one in six of the population and increasingly couples require treatment with
assisted reproductive techniques. In vitro fertilization (IVF) treatment is most commonly …