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Combining nanomedicine and immunotherapy
Conspectus Nanomedicine holds significant potential to improve the efficacy of cancer
immunotherapy. Thus far, nanomedicines, ie, 1–100 (0) nm sized drug delivery systems …
immunotherapy. Thus far, nanomedicines, ie, 1–100 (0) nm sized drug delivery systems …
Nanoparticle design strategies for enhanced anticancer therapy by exploiting the tumour microenvironment
Nanovehicles can efficiently carry and deliver anticancer agents to tumour sites. Compared
with normal tissue, the tumour microenvironment has some unique properties, such as …
with normal tissue, the tumour microenvironment has some unique properties, such as …
Collagenase nanoparticles enhance the penetration of drugs into pancreatic tumors
Overexpressed extracellular matrix (ECM) in pancreatic ductal adenocarcinoma (PDAC)
limits drug penetration into the tumor and is associated with poor prognosis. Here, we …
limits drug penetration into the tumor and is associated with poor prognosis. Here, we …
Recent progress in development of siRNA delivery vehicles for cancer therapy
Recent progress in RNA biology has broadened the scope of therapeutic targets of RNA
drugs for cancer therapy. However, RNA drugs, typically small interfering RNAs (siRNAs) …
drugs for cancer therapy. However, RNA drugs, typically small interfering RNAs (siRNAs) …
Progress of drug-loaded polymeric micelles into clinical studies
Targeting tumors with long-circulating nano-scaled carriers is a promising strategy for
systemic cancer treatment. Compared with free small therapeutic agents, nanocarriers can …
systemic cancer treatment. Compared with free small therapeutic agents, nanocarriers can …
Calcium-based biomaterials for diagnosis, treatment, and theranostics
Calcium-based (CaXs) biomaterials including calcium phosphates, calcium carbonates,
calcium silicate and calcium fluoride have been widely utilized in the biomedical field owing …
calcium silicate and calcium fluoride have been widely utilized in the biomedical field owing …
Biomolecule-assisted green synthesis of nanostructured calcium phosphates and their biomedical applications
Calcium phosphates (CaPs) are ubiquitous in nature and vertebrate bones and teeth, and
have high biocompatibility and promising applications in various biomedical fields …
have high biocompatibility and promising applications in various biomedical fields …
The effect of nanoparticle uptake on cellular behavior: disrupting or enabling functions?
A Panariti, G Miserocchi, I Rivolta - Nanotechnology, science and …, 2012 - Taylor & Francis
Nanoparticles (NPs) are materials with overall dimensions in the nanoscale range. They
have unique physicochemical properties, and have emerged as important players in current …
have unique physicochemical properties, and have emerged as important players in current …
Tumour microenvironment responsive nanoconstructs for cancer theranostic
The tumour mass is made up of not only of a heterogeneous population of cancer cells
nonetheless also a mixture of resident as well as the infiltrating host cells, secreted factors …
nonetheless also a mixture of resident as well as the infiltrating host cells, secreted factors …
Enhancing endosomal escape for nanoparticle mediated siRNA delivery
D Ma - Nanoscale, 2014 - pubs.rsc.org
Gene therapy with siRNA is a promising biotechnology to treat cancer and other diseases.
To realize siRNA-based gene therapy, a safe and efficient delivery method is essential …
To realize siRNA-based gene therapy, a safe and efficient delivery method is essential …