Nanomedicine and drug delivery systems in cancer and regenerative medicine
E Garbayo, S Pascual‐Gil… - Wiley …, 2020 - Wiley Online Library
Nanomedicine and drug delivery technologies play a prominent role in modern medicine,
facilitating better treatments than conventional drugs. Nanomedicine is being increasingly …
facilitating better treatments than conventional drugs. Nanomedicine is being increasingly …
Advanced strategies for modulation of the material–macrophage interface
Biomaterials are becoming increasingly crucial for healthcare solutions, with extensive use
in the field of tissue engineering and drug delivery. After implantation, biomaterials trigger an …
in the field of tissue engineering and drug delivery. After implantation, biomaterials trigger an …
[HTML][HTML] Mesenchymal stem cell-derived exosomes reduce A1 astrocytes via downregulation of phosphorylated NFκB P65 subunit in spinal cord injury
L Wang, S Pei, L Han, B Guo, Y Li, R Duan… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Neurotoxic A1 astrocytes are induced by inflammation after spinal cord
injury (SCI), and the inflammation-related Nuclear Factor Kappa B (NFκB) pathway may be …
injury (SCI), and the inflammation-related Nuclear Factor Kappa B (NFκB) pathway may be …
Cysteine-based redox-responsive nanoparticles for fibroblast-targeted drug delivery in the treatment of myocardial infarction
X Ji, Y Meng, Q Wang, T Tong, Z Liu, J Lin, B Li, Y Wei… - ACS …, 2023 - ACS Publications
Upon myocardial infarction (MI), activated cardiac fibroblasts (CFs) begin to remodel the
myocardium, leading to cardiac fibrosis and even heart failure. No therapeutic approaches …
myocardium, leading to cardiac fibrosis and even heart failure. No therapeutic approaches …
Exosome therapeutics for lung regenerative medicine
Exosomes are 30 to 100 nm extracellular vesicles that are secreted by many cell types.
Initially viewed as cellular garbage with no biological functions, exosomes are now …
Initially viewed as cellular garbage with no biological functions, exosomes are now …
Nasal drug delivery of anticancer drugs for the treatment of glioblastoma: preclinical and clinical trials
FA Bruinsmann, G Richter Vaz… - Molecules, 2019 - mdpi.com
Glioblastoma (GBM) is the most lethal form of brain tumor, being characterized by the rapid
growth and invasion of the surrounding tissue. The current standard treatment for …
growth and invasion of the surrounding tissue. The current standard treatment for …
Nanoparticle-mediated drug delivery for treatment of ischemic heart disease
The regenerative capacity of an adult cardiac tissue is insufficient to repair the massive loss
of heart tissue, particularly cardiomyocytes (CMs), following ischemia or other catastrophic …
of heart tissue, particularly cardiomyocytes (CMs), following ischemia or other catastrophic …
[HTML][HTML] Cardiac tissue engineering for myocardial infarction treatment
Myocardial infarction is one of the major causes of morbidity and mortality worldwide.
Current treatments can relieve the symptoms of myocardial ischemia but cannot repair the …
Current treatments can relieve the symptoms of myocardial ischemia but cannot repair the …
Micro-and nanotechnology approaches to improve Parkinson's disease therapy
PV Torres-Ortega, L Saludas, AS Hanafy… - Journal of controlled …, 2019 - Elsevier
Current therapies for Parkinson's disease are symptomatic and unable to regenerate the
brain tissue. In recent years, the therapeutic potential of a wide variety of neuroprotective …
brain tissue. In recent years, the therapeutic potential of a wide variety of neuroprotective …
[HTML][HTML] Polymeric nanoparticles in the diagnosis and treatment of myocardial infarction: Challenges and future prospects
M Karam, D Fahs, B Maatouk, B Safi, AA Jaffa… - Materials Today Bio, 2022 - Elsevier
Myocardial infarction (MI) is the leading cause of morbidity and mortality worldwide. Despite
extensive efforts to provide early diagnosis and adequate treatment regimens, detection of …
extensive efforts to provide early diagnosis and adequate treatment regimens, detection of …