From autocatalysis to survival of the fittest in self-reproducing lipid systems

MG Howlett, SP Fletcher - Nature Reviews Chemistry, 2023 - nature.com
Studying autocatalysis—in which molecules catalyse their own formation—might help to
explain the emergence of chemical systems that exhibit traits normally associated with …

Molecular ratchets and kinetic asymmetry: Giving chemistry direction

S Borsley, DA Leigh… - Angewandte Chemie …, 2024 - Wiley Online Library
Over the last two decades ratchet mechanisms have transformed the understanding and
design of stochastic molecular systems—biological, chemical and physical—in a move away …

Exploring Emergent Properties in Enzymatic Reaction Networks: Design and Control of Dynamic Functional Systems

S Ghosh, MG Baltussen, NM Ivanov, R Haije… - Chemical …, 2024 - ACS Publications
The intricate and complex features of enzymatic reaction networks (ERNs) play a key role in
the emergence and sustenance of life. Constructing such networks in vitro enables stepwise …

Out‐of‐equilibrium self‐replication allows selection for dynamic kinetic stability in a system of competing replicators

B Liu, J Wu, M Geerts, O Markovitch… - Angewandte Chemie …, 2022 - Wiley Online Library
Among the key characteristics of living systems are their ability to self‐replicate and the fact
that they exist in an open system away from equilibrium. Herein, we show how the outcome …

Competition between hydrolysis and radical ring-opening polymerization of MDO in water. Who makes the race?

BR Kordes, L Ascherl, C Rüdinger, T Melchin… - …, 2023 - ACS Publications
A major challenge in modern society is the reduction of microplastics created by polymers
having stable C–C backbones. The chemistry of radical ring-opening copolymerization of …

Coordinating external and built-in triggers for tunable degradation of polymeric nanoparticles via cycle amplification

J Tan, Z Deng, C Song, J Xu, Y Zhang… - Journal of the …, 2021 - ACS Publications
The selective activation of nanovectors in pathological tissues is of crucial importance to
achieve optimized therapeutic outcomes. However, conventional stimuli-responsive …

Controlling tin halide perovskite oxidation dynamics in solution for perovskite optoelectronic devices

S Tian, G Li, RC Turnell‐Ritson, Z Fei… - Angewandte Chemie …, 2024 - Wiley Online Library
As a leading contender to replace lead halide perovskites, tin‐based perovskites have
demonstrated ever increasing performance in solar cells and light‐emitting diodes (LEDs) …

A Peptide-Based Oscillator

D Dev, N Wagner, B Pramanik, B Sharma… - Journal of the …, 2023 - ACS Publications
Living organisms are replete with rhythmic and oscillatory behavior at all levels, to the extent
that oscillations have been termed as a defining attribute of life. Recent studies of synthetic …

Spatiotemporal regulation of hydrogel actuators by autocatalytic reaction networks

A Paikar, AI Novichkov, AI Hanopolskyi… - Advanced …, 2022 - Wiley Online Library
Regulating hydrogel actuators with chemical reaction networks is instrumental for
constructing life‐inspired smart materials. Herein, hydrogel actuators are engineered that …

A catalytically active oscillator made from small organic molecules

M Ter Harmsel, OR Maguire, SA Runikhina, ASY Wong… - Nature, 2023 - nature.com
Oscillatory systems regulate many biological processes, including key cellular functions
such as metabolism and cell division, as well as larger-scale processes such as circadian …