Aptamer-based detection of circulating targets for precision medicine

L Wu, Y Wang, X Xu, Y Liu, B Lin, M Zhang… - Chemical …, 2021 - ACS Publications
The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …

Recent advances of small extracellular vesicle biomarkers in breast cancer diagnosis and prognosis

Y Lee, J Ni, J Beretov, VC Wasinger, P Graham, Y Li - Molecular cancer, 2023 - Springer
Current clinical tools for breast cancer (BC) diagnosis are insufficient but liquid biopsy of
different bodily fluids has recently emerged as a minimally invasive strategy that provides a …

Emerging methods in biomarker identification for extracellular vesicle‐based liquid biopsy

Y Liang, BM Lehrich, S Zheng… - Journal of Extracellular …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are released by many cell types and distributed within various
biofluids. EVs have a lipid membrane‐confined structure that allows for carrying unique …

Advanced nanotechnologies for extracellular vesicle‐based liquid biopsy

L Min, B Wang, H Bao, X Li, L Zhao, J Meng… - Advanced …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are emerging as a new source of biomarkers in liquid biopsy
because of their wide presence in most body fluids and their ability to load cargoes from …

Beehive-inspired macroporous SERS probe for cancer detection through capturing and analyzing exosomes in plasma

S Dong, Y Wang, Z Liu, W Zhang, K Yi… - … applied materials & …, 2020 - ACS Publications
The protein phosphorylation status of exosomes can regulate the activity and function of
proteins related to cancer development, and it is highly possible to diagnose cancers …

Accurate cancer diagnosis and stage monitoring enabled by comprehensive profiling of different types of exosomal biomarkers: surface proteins and miRNAs

S Zhou, T Hu, G Han, Y Wu, X Hua, J Su, W **, Y Mou… - Small, 2020 - Wiley Online Library
Exosomes are recognized as promising biomarkers for early cancer diagnosis and
prognosis owing to a large amount of biological information they carried. But the key is that …

[HTML][HTML] Recent progress in aptamer-based microfluidics for the detection of circulating tumor cells and extracellular vesicles

D Sun, Y Ma, M Wu, Z Chen, L Zhang, J Lu - Journal of Pharmaceutical …, 2023 - Elsevier
Liquid biopsy is a technology that exhibits potential to detect cancer early, monitor therapies,
and predict cancer prognosis due to its unique characteristics, including noninvasive …

Advances in analytical technologies for extracellular vesicles

H Yan, Y Li, S Cheng, Y Zeng - Analytical Chemistry, 2021 - ACS Publications
Sensitive early detection, along with effective treatments and solid postoperative monitoring
remain the grand challenges in fighting against human diseases, especially cancer.(1) In …

Microfluidic platforms for extracellular vesicle isolation, analysis and therapy in cancer

CM Abreu, B Costa-Silva, RL Reis, SC Kundu… - Lab on a Chip, 2022 - pubs.rsc.org
Extracellular vesicles (EVs) are small lipidic particles packed with proteins, DNA, messenger
RNA and microRNAs of their cell of origin that act as critical players in cell–cell …

Extracellular vesicle-based liquid biopsy biomarkers and their application in precision immuno-oncology

K Asleh, V Dery, C Taylor, M Davey… - Biomarker …, 2023 - Springer
While the field of precision oncology is rapidly expanding and more targeted options are
revolutionizing cancer treatment paradigms, therapeutic resistance particularly to …