Fast-spiking parvalbumin-positive interneurons in brain physiology and Alzheimer's disease
S Hijazi, AB Smit, RE van Kesteren - Molecular Psychiatry, 2023 - nature.com
Fast-spiking parvalbumin (PV) interneurons are inhibitory interneurons with unique
morphological and functional properties that allow them to precisely control local circuitry …
morphological and functional properties that allow them to precisely control local circuitry …
Development and functional diversification of cortical interneurons
In the cerebral cortex, GABAergic interneurons have evolved as a highly heterogeneous
collection of cell types that are characterized by their unique spatial and temporal …
collection of cell types that are characterized by their unique spatial and temporal …
GABAergic interneurons in the neocortex: from cellular properties to circuits
R Tremblay, S Lee, B Rudy - Neuron, 2016 - cell.com
Cortical networks are composed of glutamatergic excitatory projection neurons and local
GABAergic inhibitory interneurons that gate signal flow and sculpt network dynamics …
GABAergic inhibitory interneurons that gate signal flow and sculpt network dynamics …
[HTML][HTML] Molecular diversity and specializations among the cells of the adult mouse brain
A Saunders, EZ Macosko, A Wysoker, M Goldman… - Cell, 2018 - cell.com
The mammalian brain is composed of diverse, specialized cell populations. To
systematically ascertain and learn from these cellular specializations, we used Drop-seq to …
systematically ascertain and learn from these cellular specializations, we used Drop-seq to …
The plasticitome of cortical interneurons
AR McFarlan, CYC Chou, A Watanabe… - Nature Reviews …, 2023 - nature.com
Hebb postulated that, to store information in the brain, assemblies of excitatory neurons
coding for a percept are bound together via associative long-term synaptic plasticity. In this …
coding for a percept are bound together via associative long-term synaptic plasticity. In this …
Hippocampal GABAergic inhibitory interneurons
KA Pelkey, R Chittajallu, MT Craig… - Physiological …, 2017 - journals.physiology.org
In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …
of the total neuronal population; however, their remarkable anatomical and physiological …
Activity-dependent gating of parvalbumin interneuron function by the perineuronal net protein brevican
E Favuzzi, A Marques-Smith, R Deogracias… - Neuron, 2017 - cell.com
Activity-dependent neuronal plasticity is a fundamental mechanism through which the
nervous system adapts to sensory experience. Several lines of evidence suggest that …
nervous system adapts to sensory experience. Several lines of evidence suggest that …
Fast-spiking, parvalbumin+ GABAergic interneurons: From cellular design to microcircuit function
Background Neuronal networks in the brain include glutamatergic principal neurons and
GABAergic interneurons (GABA, γ-aminobutyric acid). The latter may be a minority cell type …
GABAergic interneurons (GABA, γ-aminobutyric acid). The latter may be a minority cell type …
Ion channels in genetic epilepsy: from genes and mechanisms to disease-targeted therapies
J Oyrer, S Maljevic, IE Scheffer, SF Berkovic… - Pharmacological …, 2018 - Elsevier
Epilepsy is a common and serious neurologic disease with a strong genetic component.
Genetic studies have identified an increasing collection of disease-causing genes. The …
Genetic studies have identified an increasing collection of disease-causing genes. The …
The number of parvalbumin-expressing interneurons is decreased in the prefrontal cortex in autism
E Hashemi, J Ariza, H Rogers, SC Noctor… - Cerebral …, 2017 - academic.oup.com
The cognitive phenotype of autism has been correlated with an altered balance of excitation
to inhibition in the cerebral cortex, which could result from a change in the number, function …
to inhibition in the cerebral cortex, which could result from a change in the number, function …