Asthma epidemiology and risk factors

J Stern, J Pier, AA Litonjua - Seminars in immunopathology, 2020 - Springer
Asthma is a clinical syndrome that affects all age groups. Asthma prevalence worldwide has
seen a rapid increase in the latter part of the last century. Recent data has shown that …

Role of viral infections in the development and exacerbation of asthma in children

T Jartti, JE Gern - Journal of allergy and clinical immunology, 2017 - Elsevier
Viral infections are closely linked to wheezing illnesses in children of all ages. Respiratory
syncytial virus (RSV) is the main causative agent of bronchiolitis, whereas rhinovirus (RV) is …

Vitamin D: 100 years of discoveries, yet controversy continues

JC Gallagher, CJ Rosen - The lancet Diabetes & endocrinology, 2023 - thelancet.com
Over the past 100 years, many major breakthroughs and discoveries have occurred in
relation to vitamin D research. These developments include the cure of rickets in 1919, the …

Modulation of inflammatory and immune responses by vitamin D

F Colotta, B Jansson, F Bonelli - Journal of autoimmunity, 2017 - Elsevier
Vitamin D (VitD) is a prohormone most noted for the regulation of calcium and phosphate
levels in circulation, and thus of bone metabolism. Inflammatory and immune cells not only …

Vitamin D supplementation to prevent asthma exacerbations: a systematic review and meta-analysis of individual participant data

DA Jolliffe, L Greenberg, RL Hooper… - The lancet Respiratory …, 2017 - thelancet.com
Background A previous aggregate data meta-analysis of randomised controlled trials
showed that vitamin D supplementation reduces the rate of asthma exacerbations requiring …

Modulation of the immune response to respiratory viruses by vitamin D

CL Greiller, AR Martineau - Nutrients, 2015 - mdpi.com
Background: Vitamin D deficiency has been shown to be independently associated with
increased risk of viral acute respiratory infection (ARI) in a number of observational studies …

Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis

AR Martineau, DA Jolliffe, L Greenberg, JF Aloia… - 2019 - figshare.utas.edu.au
Background: Randomised controlled trials (RCTs) exploring the potential of vitamin D to
prevent acute respiratory infections have yielded mixed results. Individual participant data …

Vitamin D modulation of innate immune responses to respiratory viral infections

MT Zdrenghea, H Makrinioti… - Reviews in medical …, 2017 - Wiley Online Library
Vitamin D, in addition to its classical functions in bone homeostasis, has a modulatory and
regulatory role in multiple processes, including host defense, inflammation, immunity, and …

Vitamin D for the management of asthma

AR Martineau, CJ Cates, M Urashima… - Cochrane Database …, 2016 - cochranelibrary.com
Background Several clinical trials of vitamin D to prevent asthma exacerbation and improve
asthma control have been conducted in children and adults, but a meta‐analysis restricted …

Diet and asthma: is it time to adapt our message?

L Guilleminault, EJ Williams, HA Scott, BS Berthon… - Nutrients, 2017 - mdpi.com
Asthma is a chronic respiratory disorder which is associated with airway inflammation.
Environmental factors, in association with genetic susceptibility, play a critical role in asthma …