Recent applications of the multicomponent synthesis for bioactive pyrazole derivatives

D Becerra, R Abonia, JC Castillo - Molecules, 2022 - mdpi.com
Pyrazole and its derivatives are considered a privileged N-heterocycle with immense
therapeutic potential. Over the last few decades, the pot, atom, and step economy (PASE) …

Copper-catalyzed functionalization of enynes

Q Dherbassy, S Manna, FJT Talbot… - Chemical …, 2020 - pubs.rsc.org
The copper-catalyzed functionalization of enyne derivatives has recently emerged as a
powerful approach in contemporary synthesis. Enynes are versatile and readily accessible …

[HTML][HTML] Emerging trends and future opportunities for coumarin-heterocycle conjugates as antibacterial agents

YF Mustafa - Results in Chemistry, 2023 - Elsevier
Infectious diseases resulting from various strains of pathogenic bacteria are among the
leading causes of death and morbidity worldwide. The currently-available antibacterial …

Radical cascade multicomponent minisci reactions with diazo compounds

YL Su, GX Liu, L De Angelis, R He, A Al-Sayyed… - ACS …, 2022 - ACS Publications
Based on the strategy of polarity reversal in the generation of free radicals derived from
diazo compounds, photocatalyzed multicomponent reactions (MCRs) of nitrogen aromatic …

Magnetic nanoparticle-supported eosin Y salt [SB-DABCO@ eosin] as an efficient heterogeneous photocatalyst for the multi-component synthesis of chromeno [4, 3-b] …

M Jarrahi, B Maleki, R Tayebee - RSC advances, 2022 - pubs.rsc.org
Heterogeneous photocatalysts present a favourable procedure to realize green and eco-
friendly organic reactions. We have demonstrated an SB-DABCO@ eosin catalyst in a green …

[HTML][HTML] One-pot synthesis of dihydropyrimidinone and polyhydroquinoline derivatives with natural deep eutectic solvents (NADESs): alternative to toxic organic …

SA Jannatabadi, R Hosseinzadeh, B Maleki - Results in Chemistry, 2024 - Elsevier
Natural deep eutectic solvents (NADESs) have emerged as a novel class of solvents with
properties reminiscent of ionic liquids while offering additional advantages in terms of cost …

Multicomponent reactions for the synthesis of active pharmaceutical ingredients

Á Cores, J Clerigué, E Orocio-Rodríguez… - Pharmaceuticals, 2022 - mdpi.com
Multicomponent reactions 9i. e., those that engage three or more starting materials to form a
product that contains significant fragments of all of them), have been widely employed in the …

Recent advances in the design, synthesis and catalytic applications of triazine-based covalent organic polymers

D Yadav, SK Awasthi - Materials Chemistry Frontiers, 2022 - pubs.rsc.org
In recent times, triazine-based Covalent Organic Polymers (COPs) have emerged as a
central subclass of highly porous, N-rich organic materials, which are reported as highly …

Bioactive 2-pyridone-containing heterocycle syntheses using multicomponent reactions

D Hurtado-Rodríguez, A Salinas-Torres, H Rojas… - RSC …, 2022 - pubs.rsc.org
2-Pyridone-containing heterocycles are considered privileged scaffolds in drug discovery
due to their behavior as hydrogen bond donors and/or acceptors and nonpeptidic mimics …

Multicomponent reaction-assisted drug discovery: A time-and cost-effective green approach speeding up identification and optimization of anticancer drugs

G Graziano, A Stefanachi, M Contino… - International Journal of …, 2023 - mdpi.com
Multicomponent reactions (MCRs) have emerged as a powerful strategy in synthetic organic
chemistry due to their widespread applications in drug discovery and development. MCRs …