Recent applications of the multicomponent synthesis for bioactive pyrazole derivatives
Pyrazole and its derivatives are considered a privileged N-heterocycle with immense
therapeutic potential. Over the last few decades, the pot, atom, and step economy (PASE) …
therapeutic potential. Over the last few decades, the pot, atom, and step economy (PASE) …
Copper-catalyzed functionalization of enynes
The copper-catalyzed functionalization of enyne derivatives has recently emerged as a
powerful approach in contemporary synthesis. Enynes are versatile and readily accessible …
powerful approach in contemporary synthesis. Enynes are versatile and readily accessible …
[HTML][HTML] Emerging trends and future opportunities for coumarin-heterocycle conjugates as antibacterial agents
YF Mustafa - Results in Chemistry, 2023 - Elsevier
Infectious diseases resulting from various strains of pathogenic bacteria are among the
leading causes of death and morbidity worldwide. The currently-available antibacterial …
leading causes of death and morbidity worldwide. The currently-available antibacterial …
Radical cascade multicomponent minisci reactions with diazo compounds
Based on the strategy of polarity reversal in the generation of free radicals derived from
diazo compounds, photocatalyzed multicomponent reactions (MCRs) of nitrogen aromatic …
diazo compounds, photocatalyzed multicomponent reactions (MCRs) of nitrogen aromatic …
Magnetic nanoparticle-supported eosin Y salt [SB-DABCO@ eosin] as an efficient heterogeneous photocatalyst for the multi-component synthesis of chromeno [4, 3-b] …
Heterogeneous photocatalysts present a favourable procedure to realize green and eco-
friendly organic reactions. We have demonstrated an SB-DABCO@ eosin catalyst in a green …
friendly organic reactions. We have demonstrated an SB-DABCO@ eosin catalyst in a green …
[HTML][HTML] One-pot synthesis of dihydropyrimidinone and polyhydroquinoline derivatives with natural deep eutectic solvents (NADESs): alternative to toxic organic …
Natural deep eutectic solvents (NADESs) have emerged as a novel class of solvents with
properties reminiscent of ionic liquids while offering additional advantages in terms of cost …
properties reminiscent of ionic liquids while offering additional advantages in terms of cost …
Multicomponent reactions for the synthesis of active pharmaceutical ingredients
Á Cores, J Clerigué, E Orocio-Rodríguez… - Pharmaceuticals, 2022 - mdpi.com
Multicomponent reactions 9i. e., those that engage three or more starting materials to form a
product that contains significant fragments of all of them), have been widely employed in the …
product that contains significant fragments of all of them), have been widely employed in the …
Recent advances in the design, synthesis and catalytic applications of triazine-based covalent organic polymers
D Yadav, SK Awasthi - Materials Chemistry Frontiers, 2022 - pubs.rsc.org
In recent times, triazine-based Covalent Organic Polymers (COPs) have emerged as a
central subclass of highly porous, N-rich organic materials, which are reported as highly …
central subclass of highly porous, N-rich organic materials, which are reported as highly …
Bioactive 2-pyridone-containing heterocycle syntheses using multicomponent reactions
D Hurtado-Rodríguez, A Salinas-Torres, H Rojas… - RSC …, 2022 - pubs.rsc.org
2-Pyridone-containing heterocycles are considered privileged scaffolds in drug discovery
due to their behavior as hydrogen bond donors and/or acceptors and nonpeptidic mimics …
due to their behavior as hydrogen bond donors and/or acceptors and nonpeptidic mimics …
Multicomponent reaction-assisted drug discovery: A time-and cost-effective green approach speeding up identification and optimization of anticancer drugs
G Graziano, A Stefanachi, M Contino… - International Journal of …, 2023 - mdpi.com
Multicomponent reactions (MCRs) have emerged as a powerful strategy in synthetic organic
chemistry due to their widespread applications in drug discovery and development. MCRs …
chemistry due to their widespread applications in drug discovery and development. MCRs …