Mesenchymal stem cell-macrophage crosstalk and bone healing
Recent research has brought about a clear understanding that successful fracture healing is
based on carefully coordinated cross-talk between inflammatory and bone forming cells. In …
based on carefully coordinated cross-talk between inflammatory and bone forming cells. In …
[HTML][HTML] Homing and migration of mesenchymal stromal cells: how to improve the efficacy of cell therapy?
A De Becker, I Van Riet - World journal of stem cells, 2016 - ncbi.nlm.nih.gov
Mesenchymal stromal cells (MSCs) are currently being investigated for use in a wide variety
of clinical applications. For most of these applications, systemic delivery of the cells is …
of clinical applications. For most of these applications, systemic delivery of the cells is …
Exosomes derived from atorvastatin-pretreated MSC accelerate diabetic wound repair by enhancing angiogenesis via AKT/eNOS pathway
M Yu, W Liu, J Li, J Lu, H Lu, W Jia, F Liu - Stem cell research & therapy, 2020 - Springer
Background Mesenchymal stem cell (MSC)-derived exosomes emerge as promising
candidates for treating delayed wound healing in diabetes due to the promotion of …
candidates for treating delayed wound healing in diabetes due to the promotion of …
Donor age negatively impacts adipose tissue-derived mesenchymal stem cell expansion and differentiation
MS Choudhery, M Badowski, A Muise, J Pierce… - Journal of translational …, 2014 - Springer
Background Human adipose tissue is an ideal autologous source of mesenchymal stem
cells (MSCs) for various regenerative medicine and tissue engineering strategies. Aged …
cells (MSCs) for various regenerative medicine and tissue engineering strategies. Aged …
Dimethyloxaloylglycine-stimulated human bone marrow mesenchymal stem cell-derived exosomes enhance bone regeneration through angiogenesis by targeting the …
B Liang, JM Liang, JN Ding, J Xu, JG Xu… - Stem Cell Research & …, 2019 - Springer
Background Mesenchymal stem cell (MSC)-derived exosomes have been recognized as
new candidate agents for treating critical-sized bone defects; they promote angiogenesis …
new candidate agents for treating critical-sized bone defects; they promote angiogenesis …
Immunoprivileged no more: measuring the immunogenicity of allogeneic adult mesenchymal stem cells
Background Autologous and allogeneic adult mesenchymal stem/stromal cells (MSCs) are
increasingly being investigated for treating a wide range of clinical diseases. Allogeneic …
increasingly being investigated for treating a wide range of clinical diseases. Allogeneic …
Toward exosome-based therapeutics: isolation, heterogeneity, and fit-for-purpose potency
GR Willis, S Kourembanas, SA Mitsialis - Frontiers in cardiovascular …, 2017 - frontiersin.org
Exosomes are defined as submicron (30–150 nm), lipid bilayer-enclosed extracellular
vesicles (EVs), specifically generated by the late endosomal compartment through fusion of …
vesicles (EVs), specifically generated by the late endosomal compartment through fusion of …
Comparison of molecular profiles of human mesenchymal stem cells derived from bone marrow, umbilical cord blood, placenta and adipose tissue
JS Heo, Y Choi, HS Kim… - … journal of molecular …, 2016 - spandidos-publications.com
Mesenchymal stem cells (MSCs) are clinically useful due to their capacity for self-renewal,
their immunomodulatory properties and tissue regenerative potential. These cells can be …
their immunomodulatory properties and tissue regenerative potential. These cells can be …
Aging, inflammation, stem cells, and bone healing
Complex interactions among cells of the monocyte-macrophage-osteoclast lineage and the
mesenchymal stem cell-osteoblast lineage play a major role in the pathophysiology of bone …
mesenchymal stem cell-osteoblast lineage play a major role in the pathophysiology of bone …
Characterization of bone marrow-derived mesenchymal stem cells in aging
N Baker, LB Boyette, RS Tuan - Bone, 2015 - Elsevier
Adult mesenchymal stem cells are a resource for autologous and allogeneic cell therapies
for immune-modulation and regenerative medicine. However, patients most in need of such …
for immune-modulation and regenerative medicine. However, patients most in need of such …