Endoplasmic reticulum stress: molecular mechanism and therapeutic targets

X Chen, C Shi, M He, S **ong, X **a - Signal transduction and targeted …, 2023 - nature.com
The endoplasmic reticulum (ER) functions as a quality-control organelle for protein
homeostasis, or “proteostasis”. The protein quality control systems involve ER-associated …

Blue light exposure: ocular hazards and prevention—a narrative review

A Cougnard-Gregoire, BMJ Merle, T Aslam… - Ophthalmology and …, 2023 - Springer
Introduction Exposure to blue light has seriously increased in our environment since the
arrival of light emitting diodes (LEDs) and, in recent years, the proliferation of digital devices …

Trends in prevalence of blindness and distance and near vision impairment over 30 years: an analysis for the Global Burden of Disease Study

R Bourne, JD Steinmetz, S Flaxman… - The Lancet global …, 2021 - thelancet.com
Background To contribute to the WHO initiative, VISION 2020: The Right to Sight, an
assessment of global vision impairment in 2020 and temporal change is needed. We aimed …

Digital technology, tele-medicine and artificial intelligence in ophthalmology: A global perspective

JPO Li, H Liu, DSJ Ting, S Jeon, RVP Chan… - Progress in retinal and …, 2021 - Elsevier
The simultaneous maturation of multiple digital and telecommunications technologies in
2020 has created an unprecedented opportunity for ophthalmology to adapt to new models …

Aging, oxidative stress and degenerative diseases: mechanisms, complications and emerging therapeutic strategies

MR Chaudhary, S Chaudhary, Y Sharma, TA Singh… - Biogerontology, 2023 - Springer
Aging accompanied by several age-related complications, is a multifaceted inevitable
biological progression involving various genetic, environmental, and lifestyle factors. The …

Artificial intelligence in ophthalmology: The path to the real-world clinic

Z Li, L Wang, X Wu, J Jiang, W Qiang, H **e… - Cell Reports …, 2023 - cell.com
Artificial intelligence (AI) has great potential to transform healthcare by enhancing the
workflow and productivity of clinicians, enabling existing staff to serve more patients …

[HTML][HTML] Melatonin inhibits ferroptosis and delays age-related cataract by regulating SIRT6/p-Nrf2/GPX4 and SIRT6/NCOA4/FTH1 pathways

Y Mi, C Wei, L Sun, H Liu, J Zhang, J Luo, X Yu… - Biomedicine & …, 2023 - Elsevier
Background Cataracts are the main cause of reversible blindness worldwide. The ageing of
the lens caused by ultraviolet B (UVB) radiation is mostly related to oxidative stress (OS) …

Cataract and systemic disease: A review

MJ Ang, NA Afshari - Clinical & experimental ophthalmology, 2021 - Wiley Online Library
We review the current literature regarding the risk factors for cataract and the association
between cataract and systemic disease. Numerous epidemiologic studies have found that …

[HTML][HTML] The effect of lutein on eye and extra-eye health

S Buscemi, D Corleo, F Di Pace, ML Petroni, A Satriano… - Nutrients, 2018 - mdpi.com
Lutein is a carotenoid with reported anti-inflammatory properties. A large body of evidence
shows that lutein has several beneficial effects, especially on eye health. In particular, lutein …

[HTML][HTML] Vitamin D and ocular diseases: a systematic review

HN Chan, XJ Zhang, XT Ling, CHT Bui… - International journal of …, 2022 - mdpi.com
The contributory roles of vitamin D in ocular and visual health have long been discussed,
with numerous studies pointing to the adverse effects of vitamin D deficiency. In this paper …