Background The use of cannabis, or marijuana, for medicinal purposes is deeply rooted
though history, dating back to ancient times. It once held a prominent position in the history …

Although cannabinoids have been used for centuries for diverse pathological conditions,
recently, their clinical interest and application have emerged due to their diverse …

Background Endocannabinoids (ECs) and related N-acyl-ethanolamides (NAEs) play
important roles in stress response regulation, anxiety and traumatic memories. In view of the …

(E)-β-caryophyllene (BCP) is a natural sesquiterpene found in many essential oils of spice
(best known for contributing to the spiciness of black pepper) and food plants with …

Cannabinoids are implicated in the control of cell proliferation, but little is known about the
role of the endocannabinoid system in human malignant melanoma. This study was aimed …

Simple Summary Estrogen receptor-positive (ER+) breast cancer is the most prevalent
breast cancer subtype, accounting for 70–85% of all cases. The combination of endocrine …

Cannabidiol (CBD), derived from the plant cannabis, can be used in the cosmetics industry
for its antioxidant, anti-inflammatory, anti-wrinkle and whitening effects. However, CBD is …

Introduction The cannabinoid receptor 2 (CB2) is mainly involved in the immune system.
However, although CB2 has been reported to play an anti‐tumor function in breast cancer …

Simple Summary Glioblastoma (GBM) is a deadly cancer type of the brain with an average
of 12 months of survival after diagnosis. Current clinical therapies generally provide only a …

Introduction: Fatty acid amide hydrolase (FAAH) is the major catabolic enzyme of the
endocannabinoid N-arachidonoylethanolamine (anandamide) that, with different degrees of …