Reaching an evidence-based prognosis for personalized treatment of multiple sclerosis

D Rotstein, X Montalban - Nature Reviews Neurology, 2019 - nature.com
Personalized treatment is ideal for multiple sclerosis (MS) owing to the heterogeneity of
clinical features, but current knowledge gaps, including validation of biomarkers and …

[HTML][HTML] COVID-19-associated neurological disorders: the potential route of CNS invasion and blood-brain barrier relevance

A Achar, C Ghosh - Cells, 2020 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel human
coronavirus that has sparked a global pandemic of the coronavirus disease of 2019 (COVID …

Disease‐modifying therapies and coronavirus disease 2019 severity in multiple sclerosis

MP Sormani, N De Rossi, I Schiavetti… - Annals of …, 2021 - Wiley Online Library
Objective This study was undertaken to assess the impact of immunosuppressive and
immunomodulatory therapies on the severity of coronavirus disease 2019 (COVID‐19) in …

Humoral-and T-cell–specific immune responses to SARS-CoV-2 mRNA vaccination in patients with MS using different disease-modifying therapies

C Tortorella, A Aiello, C Gasperini, C Agrati… - Neurology, 2022 - neurology.org
Background and Objectives To evaluate the immune-specific response after full severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination of patients with …

ECTRIMS/EAN guideline on the pharmacological treatment of people with multiple sclerosis

X Montalban, R Gold, AJ Thompson… - Multiple Sclerosis …, 2018 - journals.sagepub.com
Background: Multiple sclerosis (MS) is a complex disease with new drugs becoming
available in the past years. There is a need for a reference tool compiling current data to aid …

[HTML][HTML] Ocrelizumab versus interferon beta-1a in relapsing multiple sclerosis

SL Hauser, A Bar-Or, G Comi… - … England Journal of …, 2017 - Mass Medical Soc
Background B cells influence the pathogenesis of multiple sclerosis. Ocrelizumab is a
humanized monoclonal antibody that selectively depletes CD20+ B cells. Methods In two …

Infection risks among patients with multiple sclerosis treated with fingolimod, natalizumab, rituximab, and injectable therapies

G Luna, P Al**, J Burman, K Fink… - JAMA …, 2020 - jamanetwork.com
Importance Although highly effective disease-modifying therapies for multiple sclerosis (MS)
have been associated with an increased risk of infections vs injectable therapies interferon …

COVID-19 in patients with multiple sclerosis: associations with disease-modifying therapies

AT Reder, D Centonze, ML Naylor, A Nagpal… - CNS drugs, 2021 - Springer
Abstract Background Disease-modifying therapies (DMTs) for multiple sclerosis (MS) target
immunity and have the potential to increase the risk of severe acute respiratory syndrome …

Treating multiple sclerosis and neuromyelitis optica spectrum disorder during the COVID-19 pandemic

W Brownlee, D Bourdette, S Broadley, J Killestein… - Neurology, 2020 - neurology.org
The emergence of novel coronavirus 2019 (COVID-19) 1 and the subsequent pandemic
present a unique challenge to neurologists managing patients with multiple sclerosis (MS) …

[HTML][HTML] Alterations of oligodendrocyte and myelin energy metabolism in multiple sclerosis

E López-Muguruza, C Matute - International journal of molecular sciences, 2023 - mdpi.com
Multiple sclerosis (MS) is a complex autoimmune disease of the central nervous system
(CNS), characterized by demyelination and neurodegeneration. Oligodendrocytes play a …