Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of
deaths and substantial morbidity worldwide. Intense scientific effort to understand the …

SARS-CoV-2 viral load and detection of infectious virus in the respiratory tract are the two
key parameters for estimating infectiousness. As shedding of infectious virus is required for …

The SARS-CoV-2 Delta Variant of Concern is highly transmissible and contains mutations
that confer partial immune escape. The emergence of Delta in North America caused the first …

In late 2022, China transitioned from a strict 'zero-COVID'policy to rapidly abandoning nearly
all interventions and data reporting. This raised great concern about the presumably-rapid …

Abstract Background The Omicron SARS-CoV-2 variant is responsible for a major wave of
COVID-19, with record case counts reflecting high transmissibility and escape from prior …

Background Effectively implementing strategies to curb SARS-CoV-2 transmission requires
understanding who is contagious and when. Although viral load on upper respiratory swabs …

Background: The combined impact of immunity and SARS-CoV-2 variants on viral kinetics
during infections has been unclear. Methods: We characterized 1,280 infections from the …

Background Elucidating viral dynamics within the host is important for designing public
health measures against SARS-CoV-2, particularly during the early stages of infection when …

The impact of vaccination on SARS-CoV-2 infectiousness is not well understood. We
compared longitudinal viral shedding dynamics in unvaccinated and fully vaccinated adults …

Background The global effort to vaccinate people against severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) during an ongoing pandemic has raised questions about how …