Prevention or modification of epileptogenesis after brain insults: experimental approaches and translational research

W Löscher, C Brandt, D Sibley - Pharmacological reviews, 2010 - Elsevier
Diverse brain insults, including traumatic brain injury, stroke, infections, tumors,
neurodegenerative diseases, and prolonged acute symptomatic seizures, such as complex …

Brain tumors and epilepsy: pathophysiology of peritumoral changes

MF Shamji, EC Fric-Shamji, BG Benoit - Neurosurgical review, 2009 - Springer
Epilepsy commonly develops among patients with brain tumors, frequently even as the
presenting symptom, and such patients consequently experience substantial morbidity from …

Bridging emotion theory and neurobiology through dynamic systems modeling

MD Lewis - Behavioral and brain sciences, 2005 - cambridge.org
Efforts to bridge emotion theory with neurobiology can be facilitated by dynamic systems
(DS) modeling. DS principles stipulate higher-order wholes emerging from lower-order …

Generalising the Kuramoto model for the study of neuronal synchronisation in the brain

D Cumin, CP Unsworth - Physica D: Nonlinear Phenomena, 2007 - Elsevier
In this article, we have generalised the Kuramoto model to allow one to model neuronal
synchronisation more appropriately. The generalised version allows for different connective …

Localization of VGLUT3, the vesicular glutamate transporter type 3, in the rat brain

E Herzog, J Gilchrist, C Gras, A Muzerelle… - Neuroscience, 2004 - Elsevier
We have recently identified a third subtype of glutamate vesicular transporter (VGLUT)
named VGLUT3. In the present study, we provide a detailed account of the regional and …

Disease-modifying effects of phenobarbital and the NKCC1 inhibitor bumetanide in the pilocarpine model of temporal lobe epilepsy

C Brandt, M Nozadze, N Heuchert… - Journal of …, 2010 - Soc Neuroscience
Accumulating evidence suggests that changes in neuronal chloride homeostasis may be
involved in the mechanisms by which brain insults induce the development of epilepsy. A …

Cortical hyperexcitability and epileptogenesis: understanding the mechanisms of epilepsy–part 1

RAB Badawy, AS Harvey, RAL Macdonell - Journal of Clinical …, 2009 - Elsevier
Epilepsy encompasses a diverse group of seizure disorders caused by a variety of
structural, cellular and molecular alterations of the brain primarily affecting the cerebral …

High fat diet induced-obesity facilitates anxiety-like behaviors due to GABAergic impairment within the dorsomedial hypothalamus in rats

SR de Noronha, GV Campos, AR Abreu… - Behavioural brain …, 2017 - Elsevier
Overweight and obesity are conditions associated with an overall range of clinical health
consequences, and they could be involved with the development of neuropsychiatric …

Brain tumor and seizures: pathophysiology and its implications for treatment revisited

B Schaller, SJ Rüegg - Epilepsia, 2003 - Wiley Online Library
Seizures affect∼ 50% of patients with primary and metastatic brain tumors. Partial seizures
have the highest incidence, followed by secondarily generalized, depending on histologic …

MmTX1 and MmTX2 from coral snake venom potently modulate GABA (A) receptor activity

JP Rosso, JR Schwarz, M Diaz-Bustamante, B Céard… - Biophysical …, 2015 - cell.com
GABA (A) receptors shape synaptic transmission by modulating Cl-conductance across the
cell membrane. Remarkably, animal toxins that target GABA (A) receptors have not yet been …